2dar

Solution structure of first LIM domain of Enigma-like PDZ and LIM domains proteinSolution structure of first LIM domain of Enigma-like PDZ and LIM domains protein

Structural highlights

2dar is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	Solution NMR
Ligands:
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

PDLI5_HUMAN May play an important role in the heart development by scaffolding PKC to the Z-disk region. May play a role in the regulation of cardiomyocyte expansion. Overexpression promotes the development of heart hypertrophy. Contributes to the regulation of dendritic spine morphogenesis in neurons. May restrain postsynaptic growth of excitatory synapses (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

2dar

Solution structure of first LIM domain of Enigma-like PDZ and LIM domains proteinSolution structure of first LIM domain of Enigma-like PDZ and LIM domains protein

Structural highlights

Function

Evolutionary Conservation

See Also

Contents

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Navigation menu

2dar

Solution structure of first LIM domain of Enigma-like PDZ and LIM domains proteinSolution structure of first LIM domain of Enigma-like PDZ and LIM domains protein

Structural highlights

Function

Evolutionary Conservation

See Also

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Navigation menu

Search