4iar
Crystal structure of the chimeric protein of 5-HT1B-BRIL in complex with ergotamine (PSI Community Target)Crystal structure of the chimeric protein of 5-HT1B-BRIL in complex with ergotamine (PSI Community Target)
Template:ABSTRACT PUBMED 23519210
FunctionFunction
[5HT1B_HUMAN] This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.
About this StructureAbout this Structure
4iar is a 1 chain structure. Full crystallographic information is available from OCA.
Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- Bai, F.
- Cherezov, V.
- GPCR, GPCR Network.
- Gao, X.
- Han, G W.
- Huang, X.
- Jiang, H.
- Jiang, Y.
- Katritch, V.
- Liu, W.
- Ma, J.
- McCorvy, J D.
- Melcher, K.
- Roth, B L.
- Stevens, R C.
- Vardy, E.
- Wacker, D.
- Wang, C.
- Wu, H.
- Xu, H E.
- Yang, H.
- Yang, L.
- Zhang, C.
- Zhou, E X.
- Electron transport
- Ergotamine
- Gpcr
- Gpcr dock
- Gpcr network
- Membrane protein
- Novel protein engineering
- Psi-biology
- Signaling protein
- Structural genomic