2a45
Crystal structure of the complex between thrombin and the central "E" region of fibrinCrystal structure of the complex between thrombin and the central "E" region of fibrin
Template:ABSTRACT PUBMED 16533041
About this StructureAbout this Structure
2a45 is a 10 chain structure of Fibrinogen and Thrombin with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 1qvh. The November 2006 RCSB PDB Molecule of the Month feature on Fibrin by David S. Goodsell is 10.2210/rcsb_pdb/mom_2006_11. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Pechik I, Yakovlev S, Mosesson MW, Gilliland GL, Medved L. Structural basis for sequential cleavage of fibrinopeptides upon fibrin assembly. Biochemistry. 2006 Mar 21;45(11):3588-97. PMID:16533041 doi:10.1021/bi0525369
- ↑ Pechik I, Madrazo J, Mosesson MW, Hernandez I, Gilliland GL, Medved L. Crystal structure of the complex between thrombin and the central "E" region of fibrin. Proc Natl Acad Sci U S A. 2004 Mar 2;101(9):2718-23. Epub 2004 Feb 20. PMID:14978285 doi:10.1073/pnas.0303440101