Erythrocyte binding antigen

Erythrocyte binding antigen or Duffy receptor (EBA) is a Plasmodium ligand which binds to erythrocytes. Some strains are dependent on sialic acid for binding. EBA-175 is a Plamodium ligand that binds to human erythrocytes glycophorin A in a sialic acid-dependent manner. EBA-140 is a Plamodium ligand that binds to human erythrocytes glycophorin C . For more details see Malaria Parasite Plasmodium falciparum Erythrocyte Binding Antigen 140.

spinqualitylabelsall models EBA region II (mutant) complex with sulfate and Cl- ion (PDB code 1zro) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

3D Structures of erythrocyte binding antigen3D Structures of erythrocyte binding antigen

Updated on 19-June-2024

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• EBA-175
  • 1zrl, 1zro – PfEBA region II (mutant) - Plasmodium falciparum
    
  • 2rji – PfEBA region VI
    
  • 4k2u – PfEBA + antibody
    
  • 4qex – PfEBA (mutant) + antibody
    
• EBA-140
  • 4gf2, 4jno – PfEBA (mutant)
    
• Duffy receptor region II 198-525
  • 5x6n – EBA region II – Plasmodium knowlesi
    
  • 3rrc, 4yfs – PvEBA region II – Plasmodium vivax
    
  • 5f3j, 6oan, 6oao, 6r2s – PvEBA region II + antibody
    
  • 4nuu, 4nuv – PvEBA region II + Duffy antigen/chemokine receptor