Cytochrome b5

Cytochrome b5 (CB) functions as an electron transport carrier for several membrane-bound oxygenases. . The microsomal and mitochondrial CB are membrane-bound while bacterial and other animal tissue CB are soluble.

Cytochrome b558 is a flavoprotein which is a component of NADPH oxidase^[1]
Cytochrome b562 is the the b-type cytochrome from E. coli.^[2]

3D structures of cytochrome b5

Cytochrome b5 3D structures

ReferencesReferences

↑ Sumimoto H, Sakamoto N, Nozaki M, Sakaki Y, Takeshige K, Minakami S. Cytochrome b558, a component of the phagocyte NADPH oxidase, is a flavoprotein. Biochem Biophys Res Commun. 1992 Aug 14;186(3):1368-75. PMID:1324665 doi:10.1016/s0006-291x(05)81557-8
↑ Schenkman JB, Jansson I. The many roles of cytochrome b5. Pharmacol Ther. 2003 Feb;97(2):139-52. PMID:12559387

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Michal Harel, Alexander Berchansky, Karl Oberholser

[1] Sumimoto H, Sakamoto N, Nozaki M, Sakaki Y, Takeshige K, Minakami S. Cytochrome b558, a component of the phagocyte NADPH oxidase, is a flavoprotein. Biochem Biophys Res Commun. 1992 Aug 14;186(3):1368-75. PMID:1324665 doi:10.1016/s0006-291x(05)81557-8

[2] Schenkman JB, Jansson I. The many roles of cytochrome b5. Pharmacol Ther. 2003 Feb;97(2):139-52. PMID:12559387

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