Cytochrome b5

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Cytochrome b5 (CB) functions as an electron transport carrier for several membrane-bound oxygenases[1]. . The microsomal and mitochondrial CB are membrane-bound while bacterial and other animal tissue CB are soluble.

  • Cytochrome b558 is a flavoprotein which is a component of NADPH oxidase[2]
  • Cytochrome b562 is the the b-type cytochrome from E. coli.[3]

See also Hemeproteins.

3D structures of cytochrome b5

Cytochrome b5 3D structures


Rat heme-containing cytochrome b5 (PDB entry 1b5m)

Drag the structure with the mouse to rotate

ReferencesReferences

  1. Porter TD. The roles of cytochrome b5 in cytochrome P450 reactions. J Biochem Mol Toxicol. 2002;16(6):311-6. PMID:12481306 doi:10.1002/jbt.10052
  2. Sumimoto H, Sakamoto N, Nozaki M, Sakaki Y, Takeshige K, Minakami S. Cytochrome b558, a component of the phagocyte NADPH oxidase, is a flavoprotein. Biochem Biophys Res Commun. 1992 Aug 14;186(3):1368-75. PMID:1324665 doi:10.1016/s0006-291x(05)81557-8
  3. Schenkman JB, Jansson I. The many roles of cytochrome b5. Pharmacol Ther. 2003 Feb;97(2):139-52. PMID:12559387

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