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8sze

Revision as of 08:44, 7 June 2023 by OCA (talk | contribs) (Protected "8sze" [edit=sysop:move=sysop])

Crystal structure of Yersinia pestis dihydrofolate reductase in complex with TrimethoprimCrystal structure of Yersinia pestis dihydrofolate reductase in complex with Trimethoprim

Structural highlights

8sze is a 2 chain structure with sequence from Yersinia pestis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

A0A3N4BLI0_YERPE Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.[ARBA:ARBA00025067][PIRNR:PIRNR000194]

8sze, resolution 2.50Å

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OCA
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