2d54

Crystal Structure of Methionyl tRNA Synthetase Y225A Mutant from Thermus ThermophilusCrystal Structure of Methionyl tRNA Synthetase Y225A Mutant from Thermus Thermophilus

Structural highlights

2d54 is a 1 chain structure with sequence from "flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Activity:	Methionine--tRNA ligase, with EC number 6.1.1.10
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

[SYM_THET8] Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

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OCA