4f46

Crystal structure of wild type human CD38 in complex with NAADP and ADPRPCrystal structure of wild type human CD38 in complex with NAADP and ADPRP

Structural highlights

4f46 is a 2 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:	,
Related:	4f45
Gene:	CD38 (HUMAN)
Activity:	NAD(+) nucleosidase, with EC number 3.2.2.5
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[CD38_HUMAN] Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.

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OCA

4f46

Crystal structure of wild type human CD38 in complex with NAADP and ADPRPCrystal structure of wild type human CD38 in complex with NAADP and ADPRP

Structural highlights

Function

See Also

Contents

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