2a1y

Crystal Structure of GuaC-GMP complex from Bacillus anthracis at 2.26 A Resolution.Crystal Structure of GuaC-GMP complex from Bacillus anthracis at 2.26 A Resolution.

Structural highlights

2a1y is a 1 chain structure with sequence from "bacillus_cereus_var._anthracis"_(cohn_1872)_smith_et_al._1946 "bacillus cereus var. anthracis" (cohn 1872) smith et al. 1946. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Related:	1ypf
Gene:	guaC ("Bacillus cereus var. anthracis" (Cohn 1872) Smith et al. 1946)
Activity:	GMP reductase, with EC number 1.7.1.7
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[GUAC_BACAN] Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA