Cholesterol esterase

Function Cholesterol esterase (ChoE) also named bile-salt activated lipase or sterol esterase catalyzes the hydrolytic cleavage of cholesterol, other sterol esters and triglycerides. Disease Deficiency of this enzyme causes Wolman’s disease and cholesteryl ester storage disease. Structural highlights ChoE (Hydrophobic, Polar). ChoE has the at the opening and . 3D structures of cholesterol esterase Cholesterol esterase 3D structures

spinqualitylabelsall models Glycosylated cholesterol esterase dimer complex with bile acid (PDB entry 1llf) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

3D structures of cholesterol esterase3D structures of cholesterol esterase

Updated on 12-May-2019

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• Cholesterol esterase
  • 1jmy – hChoE catalytic domain- human
    
  • 1f6w, 6h0t – hChoE catalytic domain (mutant)
    
  • 1akn – bChoE – bovine
    
  • 2bce – bChoE (mutant)
    
  • 4be9, 4be4 – OpChoE – Ophiostoma piceae
    
  • 4upd – OpChoE (mutant)
    
• Cholesterol esterase complex
  • 6h0v – hChoE (mutant) + tabun
    
  • 6h18 – hChoE (mutant) + sarin
    
  • 6h19 – hChoE (mutant) + paraoxon
    
  • 6h1a – hChoE (mutant) + VX
    
  • 1aql – bChoE + taurocholate
    
  • 1cle – CcChoE + cholesteryl linoleate – Candida cylindracea
    
  • 1llf – CcChoE + tricosanoic acid