Serpin

Serpin or serine protease inhibitor (Ser) are protease inhibitors. Ser E1 is antithrombin. Ser C1 is antithrombin. Ser A5 is protein C inhibitor. Ser A6 is a cortisol-binding globulin. Ser A8 is angiotensinogen. Ser A7 is a thyroxine-binding globulin. Ser B1 is leukocyte elastase inhibitor. Ser B3 is squamos cell carcinoma antigen 1. Ser B5 is Maspin. Ser crmA is cysteine and serine proteinase inhibitor. Ser I1 is neuroserpin. Ser A10 is protein Z-related protease inhibitor. Ser A1 is α-1 antitrypsin. Ser A3 is α 1-antichymotrypsin. Ser E1 is plasminogen activator inhibitor 1.

spinqualitylabelsall models Structure of cleaved human serpin A1. Residues 46-382 (grey), residues 383-418 (green). (PDB entry 3ndd) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

3D structures of serpin3D structures of serpin

Updated on 16-June-2015

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• Serpin
  • 1mtp, 1sng – Ser – Thermobifida fusca
• Serpin A1 see Alpha-1-antitrypsin
• Serpin A3 (α 1-antichymotrypsin)
  • 2ach, 1as4, 3caa – hSer-A3
    
  • 4caa, 1qmn, 3dlw – hSer-A3 (mutant)
    
  • 1yxa – mSer-A3N - mouse
    
• Serpin A5
  • 2ol2 – hSer-A5
    
  • 3dy0 – hSer-A5 + heparin
• Serpin A6 see Corticosteroid-binding globulin
• Serpin A7
  • 2riv – hSer-A7
    
  • 2riw – hSer-A7 + thyroxine
    
  • 2xn3 – hSer-A7 + mefenamic acid
    
  • 2xn5 – hSer-A7 + furosemide
    
  • 2xn6, 2xn7 – hSer-A7 + thyroxine-fluoresein
• Serpin A8
  • 2jp8 – hSer-A8 – NMR
    
  • 2wxw – hSer-A8
    
  • 2x0b – hSer-A8 + renin
    
  • 2wxx, 2wxy, 2wy0 – Ser-A8 – mouse
    
  • 2wxz, 2wy1 – rSer-A8
• Serpin A10
  • 3h5c, 3f1s – hSer-A10 + vitamin K-dependent protein Z
• Serpin A12
  • 4if8 – hSer-A12
    
• Serpin B1 (leukocyte elastase inhibitor)
  • 1hle – Ser-B1 – horse
    
  • 4ga7 – hSer-B1 (mutant)
    
• Serpin B3
  • 2zv6 – hSer-B3
• Serpin B5 (Maspin)
  • 1xqg, 1wz9, 1xu8 - hSer-B5
    
  • 1xqj – hSer-B5 (mutant)
    
• Serpin C1 see Antithrombin
• Ser crmA (ice inhibitor)
  • 1c8o, 1f0c – cvSer-crmA (mutant) – cowpox virus
    
• Serpin E1 see Plasminogen activator inhibitor
• Serpin E2
  • 4dy0 – hSer-E2 + heparin
• Serpin I1 (Neuroserpin)
  • 3fgq, 2f02, 3f5n – hSer-I1
    
  • 1jjo – mSer-I1
    
• Serpin K
  • 1sek – ThSer-K – Tobacco hornworm
• Serpin 1
  • 1k9o – ThSer-1 (mutant) + trypsin II
    
  • 3le2 – Ser-1 – Arabidopsis thaliana
• Serpin 2
  • 1m93 – cvSer-2
    
  • 3nda – Ser-2 – Sheep tick
    
  • 3pzf – mmSer-2 – malaria mosquito
    
  • 4ro9, 4roa, 4rob, 4rsq – mmSer-2 (mutant)
    
• Ser 4 (Serine protease inhibitor 4)
  • 4p0f, 4p0o – Ser-4 – Drosophila melanogaster