Template:STRUCTURE 1xxd

File:1xxd.png

Crystal Structure of the FXIa Catalytic Domain in Complex with mutated EcotinCrystal Structure of the FXIa Catalytic Domain in Complex with mutated Ecotin

Template:ABSTRACT PUBMED 15545266

About this StructureAbout this Structure

1xxd is a 4 chain structure of Ecotin and Factor XIa with sequence from Escherichia coli and Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1][xtra 2]

  1. Jin L, Pandey P, Babine RE, Gorga JC, Seidl KJ, Gelfand E, Weaver DT, Abdel-Meguid SS, Strickler JE. Crystal structures of the FXIa catalytic domain in complex with ecotin mutants reveal substrate-like interactions. J Biol Chem. 2005 Feb 11;280(6):4704-12. Epub 2004 Nov 15. PMID:15545266 doi:10.1074/jbc.M411309200
  2. Takamiya O, Machida S, Yamamoto M. Factor XI deficiency with a novel homozygous mutation Trp599Arg near the C-terminal region. Haematologica. 2005 Jul;90(7):999-1001. PMID:15996948

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