Ecotin

Ecotin (ECO) is a serine protease inhibitor found in the periplasm of E. coli. It is a potent anti and a reversible tight-binding inhibitor of human factor Xa. with . in thrombin heavy chain (1id5). Water molecules shown as red spheres.

spinqualitylabelsall models The dimeric E. coli ecotin (yellow) complex with thrombin heavy chain (cyan) and light chain (magenta) and Ca+2 ion (green) 1id5 Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

3D Structures of Ecotin3D Structures of Ecotin

Updated on 08-February-2023

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• Ecotin
  • 1ecy, 1ecz – ECO - Escherichia coli
    
  • 1ifg - ECO (mutant)
• Ecotin complex with protein
  • 1slu, 1slv, 1slw, 1slx, 1ezs, 1ezu, 4niy – ECO (mutant) + anionic trypsin (mutant)
    
  • 1azz – ECO + collagenase
    
  • 1id5 - ECO (mutant) + thrombin
    
  • 1n8o, 1y6t, 2y6t - ECO + chymotrypsin
    
  • 1p0s - ECO (mutant) + factor Xa
    
  • 1xx9 - ECO (mutant) + factor Xi
    
  • 1xxd, 1xxf - ECO (mutant) + factor Xi (mutant)
    
  • 1fi8 - ECO (mutant) + granzyme B
    
  • 4iw4 – ECO + mannan-binding lectin serine protease
    
  • 7cbk – ECO + elastase
    
  • 7pqo – ECO (mutant) + MASP-1
    
  • 7pqn – ECO + MASP-2