Tubulin 3D Structures
Revision as of 11:05, 8 June 2022 by Michal Harel (talk | contribs)
3D Structures of Tubulin3D Structures of Tubulin
Updated on 08-June-2022 - For a general description of the protein see Tubulin
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- α-tubulin
- α-tubulin + β-tubulin
- 5n5n – hTUBA-1A+hTUB-3 + GTP + GMPCPP – Cryo EM
- 6e7b – hTUBA-1B+hTUB-3 + GTP + GMPCPP – Cryo EM
- 7sja – hTUBA-1B+hTUB-3 + GTP – Cryo EM
- 7sj9 – hTUBA-1B+hTUB-3 + microtubule-associated protein + GTP – Cryo EM
- 5ij0, 7sj7, 7sj8 – hTUBA-1B+hTUB-3 + GTP + GDP – Cryo EM
- 5ij9 – hTUBA-1B+hTUB-3 (mutant) + GTP + GDP – Cryo EM
- 5n5n – hTUBA-1B+hTUB-5 + GTP + GMPCPP – Cryo EM
- 6e7c – hTUBA-1B+hTUB-2B + GTP + GMPCPP – Cryo EM
- 6i2i – hTUBA-1B +hTUB-5 + GTP + GMPCPP + stabilizer – Cryo EM
- 7lxb, 7m18, 7m20 - hTUBA+hTUBB + GDP + GTP + drug – Cryo EM
- 7pjf - hTUBA+hTUBB + darpin + GTP
- 1jff - bTUBA+bTUBB - bovine
- 6wvr, 6wvl, 6wvm - bTUBA+ bTUBB +GTP + GDP + stabilizer - Cryo EM
- 3j6f - pTUBA+pTUBB – pig - Cryo EM
- 3j6e, 7dmz - pTUBA+pTUBB +GMPCPP – Cryo EM
- 3j7i - pTUBA+pTUBB +GTP – Cryo EM
- 7sgs - pTUBA+pTUBB + esconsin + GTP – Cryo EM
- 6o2r, 6o2q, 6o2s, 6o2t, 5xxw, 5xxv, 5xxt, 6evx, 6evz, 6ew0, 6dpv - pTUBA+pTUBB +GTP + GDP – Cryo EM
- 6evy, 6dpw - pTUBA+pTUBB + GTPgS + GTP – Cryo EM
- 5xxx, 7dn0 - pTUBA+pTUBB +GTP + GMPCPP – Cryo EM
- 6dpu, 6evw - pTUBA+pTUBB + GMPCPP + GTP – Cryo EM
- 1tub - pTUBA+pTUBB – electron diffraction
- 5w3f, 5w3j - yTUBA+ yTUBB +GTP + GDP – yeast - Cryo EM
- 5w3h - yTUBA+ yTUBB +GTP + GDP + stabilizer - Cryo EM
- 2btq – PdTUBA+PdTUBB
- 6e88 - TUBA+ TUBB +GTP + GDP – Caenorhabditis elegans - Cryo EM
- 6ve7, 6u42 – TUBA + TUBB + GTP + GDP + stabilizer – Chlamydomonas reinhardtii - Cryo EM
- 6u0h, 5ubq, 5ucy - TtTUBA+TUBB + GTP + GDP – Tetrahymena thermophila - Cryo EM
- 7miz - TUBA+TUBB + SPM1 + PDI + GTP + GDP – Toxoplasma gondii - Cryo EM
- 5n5n – hTUBA-1A+hTUB-3 + GTP + GMPCPP – Cryo EM
- α-tubulin + β-tubulin complexes with stathmin
- 5lp6 – bTUBA1B +bTUBB2B +stathmin-4 + protein
- 3du7, 3e22, 1z2b, 1sa0, 1sa1, 1ffx – bTUBA1C+bTUBB2B+stathmin-4
- 5la6 - bTUBA+bTUBB+stathmin-4 + protein + GDP + GTP + ATP derivative + benzodioxol derivative
- 7jfr - bTUBA+bTUBB+stathmin-4 + protein + GDP + GTP + ATP derivative + auristatin
- 6xes, 6xet, 7lz7, 7lz8 – pTUBA1B +pTUBB +stathmin-4 + inhibitor
- 3hkb, 3hkc, 3hkd, 3hke, 3n2g, 3n2k, 3ryc, 3ryf, 3ryh, 3ryi, 4eb6 – sTUBA+sTUBB+stathmin-4 – sheep
- 4f61 - sTUBA+sTUBB+stathmin-like protein R4
- 3ut5 - sTUBA+sTUBB+stathmin-4 + vinca peptide
- 4eb6 - sTUBA+sTUBB+stathmin-4
- 4f6r - sTUBA+sTUBB+stathmin-like protein R1 + ankyrin repeat protein
- 6tde - sTUBA+sTUBB+stathmin-4 + GDP + GTP
- 6h9b - sTUBA+sTUBB+stathmin-4 + GDP + GTP + quinoline derivative
- 5lp6 – bTUBA1B +bTUBB2B +stathmin-4 + protein
- α-tubulin + β-tubulin complexes with stathmin and tubulin Tyr-ligase
- 4o2a, 4iij, 4i55 - bTUBA+bTUBB+stathmin-4 + TUB-Tyr ligase
- 4wbn, 6s9e, 6gze, 6i5c - bTUBA+bTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative
- 5xlz - bTUBA+bTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + anthracene derivative
- 6qqn, 6knz - bTUBA+bTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + pyrimidine derivative
- 6hx8, 6gj4, 6y6d – bTUBA1B+bTUBB2B+stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + quinoline derivative
- 6ses, 7au5, 7ogn – bTUBA1B+bTUBB2B+stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + drug
- 6k9v, 6jcj, 6fkl, 6fkj, 6f7c, 5z4p, 5yz3, 5nfz, 5lyj, 6y4m, 6y4n, 7cbz, 7cpd, 7cpq, 7e4p, 7e4q, 7e4r, 7e4y, 7e4z – bTUBA + bTUBB + stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + inhibitor
- 5ng1 – bTUBA + bTUBB + stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + inhibitor + stabilizer
- 6fjf, 4tv8 - bTUBA+bTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + maytansine
- 4tuy, 4o4h, 4o4i, 4o4j, 4o4l, 4i50, 4i4t, 6fii, 6fjm, 6gf3, 6qtn, 5jh7, 5bmv, 5la6, 5osk, 5jvd, 5gon, 5xlt, 5xaf, 5xag – bTUBA + bTUBB +stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + drug
- 5iyz, 5j2t, 5j2u, 4tv9, 4yj2, 4yj3, 2xrp, 7jfr – bTUBAB1 +bTUBBB2 +stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + auristatin anti-mitotics
- 4o2b - bTUBA+bTUBB+stathmin-4 + TUB-Tyr ligase + colchicine
- 4ihj - bTUBA+bTUBB+stathmin-4 + tubulin Tyr-ligase + ADP
- 7en3 - bTUBA+bTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + toxin
- 4x1i, 4x1k, 4x1y, 4x20 - sTUBA+bTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + dolastatin + colchicine
- 5eyp - sTUBA+sTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + colchicine
- 4zhq, 4zi7, 4zol – pTUBAB1 +pTUBBB2 +stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + valinamide derivative
- 6o5n - pTUBA+pTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + i
- 6x1e, 6x1e, 6x1f, 7cld, 7cnm, 7cnn, 7dad, 7dae, 7daf, 7dp8, 7emj - pTUBA+pTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + drug
- 7cno, 7l05 - pTUBA+pTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + toxin
- 5jqg, 5xp3 - pTUBA+pTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative
- 6o61, 6o5m - pTUBA+pTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + imidazole derivative
- 6nng, 6eg5 - pTUBA+ pTUBB+stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + pyrimidine derivative
- 6n47 - pTUBA+ pTUBB+stathmin-4 + protein + GDP + GTP + ATP derivative + pyrimidine derivative
- 5jcb, 5ca0, 5yl2, 5ylj, 5yls - pTUBA+ pTUBB+stathmin-4 + protein + GDP + GTP + ATP derivative + depolymerizer
- 5cb4, 5xhc, 5xi5, 5xi7, 7cda, 7ce6, 7ce8, 7cek, 7db9, 7dba. 7dbb, 7dbc. 7dbd, 7exc – pTUBA + pTUBB + stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + inhibitor
- 6kpp – pTUBA1B + pTUBB + stathmin-4 + TUB-Tyr ligase + GDP + GTP + benzofuran derivative
- 5xiw – pTUBA + pTUBB +stathmin-4 + TUB-Tyr ligase + GDP + GTP + anti-gout agent
- 6pc4, 5xkg, 5xkh, 5xke, 5xkf – pTUBA + pTUBB +stathmin-4 + TUB-Tyr ligase + GDP + GTP + anti-tumor agent
- 5c8y, 6d88, 6br1, 6brf, 6bry, 6bs2, 5yl4 – pTUBA + pTUBB +stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + anti-tumor agent
- 5ezy - pTUBA+ bTUBB+stathmin-4 + protein + GDP + GTP + ATP derivative + stabilizer
- 5zxh - pTUBA+ bTUBB (mutant) +stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + imidazole derivative
- 5z4u, 6agk, 5h7o, 5h74 – pTUBA + bTUBB + stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + inhibitor
- 5fnv – cTUBA + rTUBB +stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + anti-tumor agent - chicken
- 5ca1 – pTUBA + cTUBB + stathmin-4 + TUB-Tyr ligase + GDP + GTP + ATP derivative + inhibitor
- 4o2a, 4iij, 4i55 - bTUBA+bTUBB+stathmin-4 + TUB-Tyr ligase
- α-tubulin + β-tubulin complex with kinesin
- 2p4n - hTUBA+hTUBB+kinesin heavy chain
- 6ojq – hTUBA1B+hTUBB2B+kinesin -1 heavy chain + GTP + GMPCPP – Cryo EM
- 2wbe – bTUBA1D+bTUBB2B+kinesin+AMPPNP
- 3dco - bTUBA+bTUBB+kinesin-like NOD
- 4ck5, 4ck6, 4ck7 - bTUBA+bTUBB+kinesin-like KIF11 motor domain
- 5hnw, 5hnx, 5hny, 5hnz – bTUBAB1 +bTUBBB2 +kinesin-14 + GDP + GTP + stabilizer
- 3edl - bTUBA1D+bTUBB2B+kinesin motor domain
- 4hna - bTUBA+bTUBB + kinesin heavy chain + ankyrin repeat protein
- 4uxo, 4uxp, 4uxr, 4uxs, 4uxy - bTUBA+bTUBB + kinesin motor domain + GDP + GTP + stabilizer – Cryo EM
- 4uxt, 4uy0 - bTUBA+bTUBB + kinesin heavy chain + GDP + GTP + stabilizer – Cryo EM
- 3j2u - bTUBA+bTUBB+kinesin-like KLP10A head domain
- 4aqv, 4aqw - bTUBA+bTUBB+kinesin-like KIF11 – Cryo EM
- 4atx - bTUBA1D+bTUBB2B+kinesin motor domain – Cryo EM
- 6zpi - bTUBA1D+bTUBB2B+kinesin motor domain Kif15 – Cryo EM
- 5mm7 - bTUBA1A+bTUBB +kinesin-4 motor domain + GTP + GDP + ANP + stabilizer – Cryo EM
- 5mm4 - bTUBA1A+bTUBB +kinesin-5 motor domain + GTP + GDP + ANP + stabilizer – Cryo EM
- 5ogc, 5oam - bTUBA+pTUBB+kinesin-like KIF18A + GTP + GDP + stabilizer – Cryo EM
- 5ocu - bTUBA+pTUBB+kinesin-like KIF18A + GTP + GDP + ANP + stabilizer – Cryo EM
- 2hxf - pTUBA+pTUBB+kinesin-like KIF1A+AMPPNP
- 6bbn - pTUBA+pTUBB+kinesin-like KIF2A + darpin + ANP + GDP + GTP
- 3j6h - pTUBA+pTUBB +GMPCPP + kinesin heavy chain – Cryo EM
- 3j8x - pTUBA+pTUBB +GDP + GTP + kinesin heavy chain – Cryo EM
- 3j8y - pTUBA+pTUBB +GDP + GTP + ATP + kinesin heavy chain – Cryo EM
- 2hxh - pTUBA+pTUBB+kinesin-like KIF1A+ADP
- 1ia0 - pTUBA+pTUBB+kinesin-like KIF1A+ATP
- 6tiw - pTUBA+pTUBB+kinesin-like KIF11 + GMPCPP + quinoline derivative – Cryo EM
- 6ta4 - pTUBA+pTUBB+kinesin-like KIF11 + GTP + GMPCPP + ANP – Cryo EM
- 6ta3 - pTUBA+pTUBB+kinesin-like KIF11 + GTP + GMPCPP + quinolin derivative – Cryo EM
- 6b0i, 6b0i, 6b0c - pTUBA+pTUBB+kinesin-like KLP10A + GTP + GDP + stabilizer – Cryo EM
- 6vpp - pTUBA+pTUBB+kinesin-like KLP61F + GTP + GDP – Cryo EM
- 6vpo - pTUBA+pTUBB+kinesin-like KLP61F + GTP + GDP + ANP – Cryo EM
- 7nb8 - pTUBA+pTUBB+kinesin-5 motor domain + GTP + G2P – Cryo EM
- 7nba - pTUBA+pTUBB+kinesin-5 motor domain + GTP + G2P + ANP – Cryo EM
- 6mlr - pTUBA+pTUBB+kinesin-like KIF7 + GTP + GDP + ANP + stabilizer – Cryo EM
- 6mlq - pTUBA+pTUBB+kinesin-like KIF7 + GTP + GDP + ADP + stabilizer – Cryo EM
- 7lvr - pTUBA+pTUBB+kinesin-like KIF14 + GTP + GDP + ADP – Cryo EM
- 6wwe, 6wwf, 6wwg, 6wwh, 6wwi, 6wwj, 6wwk, 6wwl, 6wwm, 6wwn, 6wwo, 6wvp, 6wwq, 6wwr, 6wws, 6wwu, 6wwv, 7lvq - pTUBA+pTUBB+kinesin-like KIF14 + GTP + GDP + ANP – Cryo EM
- 6s8m - pTUBA+pTUBB+kinesin-like CUT7 + GTP + GDP + ANP – Cryo EM
- 4lnu - sTUBA+sTUBB + ankyrin repeat protein + GDP + GTP + kinesin heavy chain
- 5mlv - fyTUBA+ fyTUBB+kinesin-like CUT7 + GTP + GDP + ANP – fission yeast - Cryo EM
- 2p4n - hTUBA+hTUBB+kinesin heavy chain
- α-tubulin + β-tubulin other complexes
- 6s8l, 6s8k - hTUBA+hTUBB + ankyrin repeat protein + GDP + GTP + plinabulin
- 6rza - hTUBA+hTUBB +GTP + GDP + stabilizer + dynein heavy chain – Cryo EM
- 6qvj, 6qus - hTUBA+hTUBB +GTP + GDP + stabilizer + CAMSAP1 – Cryo EM
- 6qve - hTUBA+hTUBB + GTP + GDP + stabilizer + protein – Cryo EM
- 6quy - hTUBA+hTUBB +GTP + GDP + stabilizer + CKK – Cryo EM
- 6wsl - hTUBA1A+hTUBB3 + small vasohibin-binding protein + tubulinyl-Tyr carboxypeptidase + GMPCPP + GTP – Cryo EM
- 7nvn – hTUB2A in TRIC coplex + nanobody – Cryo EM
- 6zwb, 6zwc, 7z01, 7z02 - bTUBA+bTUBB + darpin + photoswitch + GTP + GDP
- 7alr, 7odn - bTUBA+bTUBB + darpin + drug + GTP + GDP
- 7z7d - bTUBA+bTUBB+GDP+GTP+ drug
- 1tvk - bTUBA+bTUBB+GDP+GTP+ drug – electron crystallography
- 3iz0 - bTUBA+bTUBB+hNDC80/SPC25+hNUF2/SPC24 – electron microscopy
- 3j1t, 3j1u - bTUBA+bTUBB+ dynein
- 4atu - bTUBA1D+bTUBB2B+doublecortin – Cryo EM
- 6rev, 6rf2, 6rf8, 6rfd - bTUBA1B+bTUBB2B + doublecortin + GDP + GTP – Cryo EM
- 5itz - bTUBA+bTUBB + CENP-J + darpin + GTP + GDP + colchicine
- 5eib - bTUBA+bTUBB + CENP-J peptide + darpin + GTP + GDP
- 7ac5 - bTUBA+ bTUBB + stathmin-like domain R1 + darpin + GDP + GTP
- 6kiq, 6kio – pTUBA1A+pTUBB + dynein heavy chain – Cryo EM
- 3j6p, 6rzb - pTUBA+pTUBB +GTP + GDP + stabilizer + dynein heavy chain – Cryo EM
- 3j6g - pTUBA+pTUBB +GTP + GDP + stabilizer – Cryo EM
- 5kmg - pTUBA+pTUBB + protein regulator + GTP + GDP – Cryo EM
- 6cvj, 6cvn, 7pqc, 7pqp – pTUBA1B+pTUBB + tau + GTP + GDP – Cryo EM
**6mzg, 6mzf, 6mze - pTUBA+pTUBB + STU2P + darpin + GTP + GDP - 5syg, 5syf, 5sye, 5syc - pTUBA+pTUBB + STU2P + stabilizer + GTP + GDP
- 6gx7 - sTUBA+sTUBB + alpharep + low calcium response + GTP
- 6gwd, 6gwc - sTUBA+sTUBB + alpharep + GTP + GDP
- 7q1e, 7q1f, 7z0f, 7z0g - sTUBA+sTUBB + alpharep + CENP-J + GTP + GDP
- 6bjc, 6gvn - sTUBA+sTUBB + darpin + GTP
- 6gvm - sTUBA+sTUBB + stathmin-like domain R1 + darpin + GDP + GTP
- 4drx - sTUBA+sTUBB + ankyrin repeat protein
- 4ffb, 4u3j - yTUBA+TUBB (mutant) + protein STU2
- 5mjs - fyTUBA+ fyTUBB + MAL3 + GTP + GDP + ANP - Cryo EM
- 6u0u, 6u0t - TtTUBA+TUBB+ profilament ribbon protein + GTP + GDP - Cryo EM
- 7mwg - TtTUBA+TUBB + GTP + GDP - Cryo EM
- 7pje - TtTUBA+TtTUBB + darpin + GTP
- 7n32 - TtTUBA+TtTUBB + dynein + GTP + GDP – Cryo EM
- 6s8l, 6s8k - hTUBA+hTUBB + ankyrin repeat protein + GDP + GTP + plinabulin
- γ-tubulin
- 6v5v, 7qj0, 7qj1, 7qj2, 7qj3, 7qj4, 7qj5, 7qj6, 7qj7, 7qj8, 7qj9, 7qja, 7qjb, 7qjc, 7qjd – hTUBG1 + GDP – Cryo EM
- 7qje – hTUBG1 + TUBG components 4,5,6 – Cryo EM
- 3cb2 – hTUBG1+GDP
- 1z5v - hTUBG1+GTPgS
- 1z5w - hTUBG1+GTP
- 6v6b – hTUBG2 + TUBG3 – Cryo EM
- 6x0v – hTUBG2 + mitotic-spindle organizing protein + Cep215 – Cryo EM
- 3rip – hTUBG4
- 6v69 – hTUBG4 + TUBG5 – Cryo EM
- 6x0u – hTUBG3 + TUBG6 + mitotic spindle organizing protein – Cryo EM
- 6l81 – hTUBG5 + mitotic-spindle organizing protein
- 6v6c – hTUBG6 – Cryo EM
- 6v6s – hTUBG + ADP + GDP – Cryo EM
- 6tf9 – TUBG – frog - Cryo EM
- 7m2w, 7m2x, 7m2y, 7m2z – yTUBG + SPC97 + SPC98 - Cryo EM
- 6l80 – fyTUBG subunit Mod21 + mitotic-spindle organizing protein
- 7anz – TUBG – Candida albicans - Cryo EM
- 6v5v, 7qj0, 7qj1, 7qj2, 7qj3, 7qj4, 7qj5, 7qj6, 7qj7, 7qj8, 7qj9, 7qja, 7qjb, 7qjc, 7qjd – hTUBG1 + GDP – Cryo EM