Integrin 3D structures

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3D structures of integrin3D structures of integrin

Updated on 05-October-2021

    • 4irz - hIG + antibody
  • IG α-4 (CD49d) + IG β-7
    • 3v4p - hIG headpiece (mutant) + antibody + Mg
    • 3v4v - hIG headpiece (mutant) + antibody + inhibitor + Mg
  • IG α-5 (CD49e) + IG β-1 (CD29)
    • 7nxd – hIG + Mg – Cryo-EM
    • 7nwl – hIG + fibronectin + laminin – Cryo-EM
    • 4wjk - hIG headpiece (mutant) + Mg
    • 4wk0, 4wk2, 4wk4 - hIG headpiece (mutant) + peptide + Mg
    • 3vi3 - hIG headpiece + antibody + Mg
    • 3vi4 - hIG headpiece + antibody + peptide + Mg
  • IG α-5 (CD49e) β-3 (CD61) ectodomain
  • IG α-5 β-6
    • 4um8 – hIG headpiece (mutant) + Ni
    • 5ffg – hIG headpiece + Ca
    • 4um9 – hIG headpiece (mutant) + Mg + transforming growth factor β 3
    • 5neu, 5net, 5ner, 5nem – hIG headpiece + foot-and-mouth virus – Cryo EM
    • 5ffo – hIG headpiece + TGF-beta-1
  • IG α-L
    • 4ixd – hIG I domain
    • 5e6s, 5e6r – hIG AI, headpiece,pocket domains + Mg
    • 2m3e – hIG transmembrane domain - NMR
  • IG α-L β-2
    • 5e6u – hIG headpiece (mutant) + Ni
  • IG α-V β-3
    • 6mk0 – hIG + antagonist
    • 6msl – hIG + cysteine knot protein
    • 6msu – hIG + EETI-II
    • 6naj – hIG + fibronectin
  • IG α-V β-8
    • 6djp, 6ujb, 6ujc – hIG + antibody – Cryo EM
    • 6om1 – hIG (mutant)
    • 6om2 – hIG (mutant) + Protgf-b1 RGD peptide
    • 6uja – hIG + Protgf-b1 RGD – Cryo EM
  • IG α-X
    • 2luv – hIG cytoplasmic domain – NMR
  • IG α-X β-2 (CD18)
  • IG β-1D
    • 3g9w – hIG cytoplasmic tail + talin 2 F2-F3 domain
  • IG β-2 (CD18)
    • 2p26, 2p28, 5e6w – hIG phe2 + phe3 domains
    • 1yuk – hIG chain A PSI domain + chain B I-EGF domain
    • 5zaz – hIG transmembrane domain - NMR
  • IG β-3 (CD61)
    • 1s4x, 2kv9, 2ljd, 2lje, 2ljf – hIG cytoplasmic domain – NMR
    • 2rmz, 2rn0 – hIG transmembrane domain – NMR
    • 2l91 - hIG transmembrane domain (mutant) – NMR
    • 2l1c – hIG cytoplasmic tail + SHC
    • 2mtp – hIG cytoplasmic tail (mutant) + hIG α-2 β peptide+ filamin rod domain
  • IG β-4 (CD104; Gp150)
    • 2f7q, 3f7r, 1qg3, 3f7q, 4wtw, 4wtx - hIG fibronectin type III domain
    • 2yrz – hIG fibronectin type III domain – NMR
    • 3f7p, 4q58 - hIG fibronectin type III domain + plectin-1
    • 6gvl - hIG fibronectin type III domain + dystonin
    • 6gvk - hIG fibronectin type III domain (mutant) + dystonin
    • 3fq4, 3fso, 3h6a – hIG Calx-β domain
    • 6hyf - rIG fibronectin type III domain
  • IG β-7
    • 2brq, 2jf1 – hIG cytoplasmic tail + filamin rod domain

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Michal Harel