3uwp

From Proteopedia
Revision as of 00:19, 6 August 2016 by OCA (talk | contribs)
Jump to navigation Jump to search

Crystal structure of Dot1l in complex with 5-iodotubercidinCrystal structure of Dot1l in complex with 5-iodotubercidin

Structural highlights

3uwp is a 1 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , ,
Gene:DOT1L, KIAA1814, KMT4 (HUMAN)
Activity:Histone-lysine N-methyltransferase, with EC number 2.1.1.43
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[DOT1L_HUMAN] Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA.

See Also

3uwp, resolution 2.05Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA