Adenylate kinase
Adenylate kinase (ADK) is a phosphotransferase which catalyzes the interconversion of ADP to ATP+AMP. ADK is important in cellular energy homeostasis. The images at the left and at the right correspond to one representative ADK, i.e. the crystal structure of Adenylate kinase from Desulfovibrio gigas (3l0p).
3D Structures of Adenylate kinase3D Structures of Adenylate kinase
3l0p – DgADK+Fe – Desulfovibrio gigas
3l0s – DgADK+Co
2xb4 – DgADK+Zn
3hpq, 3hpr, 1e4v, 1e4y – EcADK (mutant)+AP5 – Escherichia coli
4ake – EcADK
1ank – EcADK+AMP+AMPPNP
1ake – EcADK+AP5
3h86 – ADK+AP5 – Methanococcus maripaludis
3fb4 – ADK+Zn+AP5 – Marinibacillus marinus
3dkv, 3dl0, 1p3j - BsADK+Zn+AP5 – Bacillus subtilis
2qaj, 2oo7, 2p3s, 2ori, 2osb, 2eu8 – BsADK (mutant)+Zn+AP5
3gmt – ADK – Burkholderia pseudodomallei
3cm0 – ADK – Thermus thermophilus
2rgx - AaADK+Zn+AP5 – Aquifex aeolicus
2rh5 – AaADK
3be4 – ADK+AP5 – Cryptosporidium parvum
2cdn – MtADK+ADP – Mycobacterium tuberculosis
1p4s - MtADK
2c9y – hADK 2+bis-adenosine tetraphosphate – human
2ar7 – hADK 4
2bbw – hADK 4+diguanosine pentaphosphate
2bwj – hADK 5+AMP
1s3g - ADK+Zn+AP5 – Bacillus globisporus
1kht – ADK+AMP – Methanococcus voltae
1ki9 – ADK – Methanococcus thermolithotrophicus
1nks – ADK+AMP+ADP – Sulfolobus acidocaldarius
1zak – ADK+AP5 – maize
1zip, 1zin – ADK+Zn+Mn+AP5 – Bacillus stearothermophilus
1ak2, 2ak2 – bADK – bovine
2ak3 – bADK+AMP
1dvr – yADK (mutant)+ATP analog – yeast
1aky, 2aky – yADK+AP5
3aky - yADK (mutant)+AP5
3adk – ADK - pig