Template:STRUCTURE 2wo8

File:2wo8.png

MMP12 COMPLEX WITH A BETA HYDROXY CARBOXYLIC ACIDMMP12 COMPLEX WITH A BETA HYDROXY CARBOXYLIC ACID

Template:ABSTRACT PUBMED 19703773

About this StructureAbout this Structure

2wo8 is a 4 chain structure of Elastase and Matrix metalloproteinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. Holmes IP, Gaines S, Watson SP, Lorthioir O, Walker A, Baddeley SJ, Herbert S, Egan D, Convery MA, Singh OM, Gross JW, Strelow JM, Smith RH, Amour AJ, Brown D, Martin SL. The identification of beta-hydroxy carboxylic acids as selective MMP-12 inhibitors. Bioorg Med Chem Lett. 2009 Oct 1;19(19):5760-3. Epub 2009 Aug 6. PMID:19703773 doi:10.1016/j.bmcl.2009.07.155

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