1e37
PORCINE PANCREATIC ELASTASE COMPLEXED WITH (3S, 4S)N-PARA-NITROBENZENESULPHONYL -3-ETHYL-4-(CARBOXYLIC ACID)PYRROLIDIN-2-ONE SOAKED IN PH 9 BUFFER FOR 1 MINUTEPORCINE PANCREATIC ELASTASE COMPLEXED WITH (3S, 4S)N-PARA-NITROBENZENESULPHONYL -3-ETHYL-4-(CARBOXYLIC ACID)PYRROLIDIN-2-ONE SOAKED IN PH 9 BUFFER FOR 1 MINUTE
About this StructureAbout this Structure
1e37 is a 1 chain structure of Elastase with sequence from Sus scrofa. Full crystallographic information is available from OCA.
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ReferenceReference
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- ↑ Wright PA, Wilmouth RC, Clifton IJ, Schofield CJ. 'pH-jump' crystallographic analyses of gamma-lactam-porcine pancreatic elastase complexes. Biochem J. 2000 Oct 15;351 Pt 2:335-40. PMID:11023818
- ↑ Wilmouth RC, Kassamally S, Westwood NJ, Sheppard RJ, Claridge TD, Aplin RT, Wright PA, Pritchard GJ, Schofield CJ. Mechanistic insights into the inhibition of serine proteases by monocyclic lactams. Biochemistry. 1999 Jun 22;38(25):7989-98. PMID:10387042 doi:10.1021/bi990098y
- ↑ Wilmouth RC, Westwood NJ, Anderson K, Brownlee W, Claridge TD, Clifton IJ, Pritchard GJ, Aplin RT, Schofield CJ. Inhibition of elastase by N-sulfonylaryl beta-lactams: anatomy of a stable acyl-enzyme complex. Biochemistry. 1998 Dec 15;37(50):17506-13. PMID:9860865 doi:10.1021/bi9816249
- ↑ Wilmouth RC, Clifton IJ, Robinson CV, Roach PL, Aplin RT, Westwood NJ, Hajdu J, Schofield CJ. Structure of a specific acyl-enzyme complex formed between beta-casomorphin-7 and porcine pancreatic elastase. Nat Struct Biol. 1997 Jun;4(6):456-62. PMID:9187653
- ↑ Meyer E, Cole G, Radhakrishnan R, Epp O. Structure of native porcine pancreatic elastase at 1.65 A resolutions. Acta Crystallogr B. 1988 Feb 1;44 ( Pt 1):26-38. PMID:3271103