8tvl: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
← Older edit
No edit summary
No edit summary
 
Line 8: Line 8:
</table>
</table>
== Function ==
== Function ==
[https://www.uniprot.org/uniprot/Q6V4L8_STRPY Q6V4L8_STRPY]  
[https://www.uniprot.org/uniprot/PAM_STRPY PAM_STRPY] Binds to human plasminogen (and plasmin) via its kringle repeats. Also binds to albumin, immunoglobulin G and fibrinogen. Could provide the bacteria with a mechanism for invasion, as streptococcal-bound plasmin could permit tissue penetration.
__TOC__
__TOC__
</StructureSection>
</StructureSection>

Latest revision as of 16:16, 21 August 2024

Plasminogen binding group A streptococcus M-like protein from AP53 bound to human plasminogenPlasminogen binding group A streptococcus M-like protein from AP53 bound to human plasminogen

Structural highlights

8tvl is a 1 chain structure with sequence from Streptococcus pyogenes. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 3.8Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PAM_STRPY Binds to human plasminogen (and plasmin) via its kringle repeats. Also binds to albumin, immunoglobulin G and fibrinogen. Could provide the bacteria with a mechanism for invasion, as streptococcal-bound plasmin could permit tissue penetration.

8tvl, resolution 3.80Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=8tvl&oldid=4244188"