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Plasminogen binding group A streptococcus M-like protein from AP53 bound to human plasminogenPlasminogen binding group A streptococcus M-like protein from AP53 bound to human plasminogen
Structural highlights
FunctionPAM_STRPY Binds to human plasminogen (and plasmin) via its kringle repeats. Also binds to albumin, immunoglobulin G and fibrinogen. Could provide the bacteria with a mechanism for invasion, as streptococcal-bound plasmin could permit tissue penetration. |
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