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==tRNA 2-phosphotransferase (Tpt1) from Pyrococcus horikoshii in complex with 5'-AMP== | |||
<StructureSection load='8tkb' size='340' side='right'caption='[[8tkb]], [[Resolution|resolution]] 1.71Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8tkb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii_OT3 Pyrococcus horikoshii OT3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8TKB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8TKB FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.71Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8tkb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8tkb OCA], [https://pdbe.org/8tkb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8tkb RCSB], [https://www.ebi.ac.uk/pdbsum/8tkb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8tkb ProSAT]</span></td></tr> | ||
[[Category: Dantuluri | </table> | ||
[[Category: Shuman | == Function == | ||
[https://www.uniprot.org/uniprot/KPTA_PYRHO KPTA_PYRHO] Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase (By similarity). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Pyrococcus horikoshii OT3]] | |||
[[Category: Dantuluri S]] | |||
[[Category: Jacewicz A]] | |||
[[Category: Shuman S]] | |||
Latest revision as of 08:53, 19 June 2024
tRNA 2-phosphotransferase (Tpt1) from Pyrococcus horikoshii in complex with 5'-AMPtRNA 2-phosphotransferase (Tpt1) from Pyrococcus horikoshii in complex with 5'-AMP
Structural highlights
FunctionKPTA_PYRHO Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1-2-cyclic phosphate (APPR>P). May function as an ADP-ribosylase (By similarity). |
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