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tRNA 2-phosphotransferase (Tpt1) from Pyrococcus horikoshii in complex with 5'-AMPtRNA 2-phosphotransferase (Tpt1) from Pyrococcus horikoshii in complex with 5'-AMP
Structural highlights
FunctionKPTA_PYRHO Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1-2-cyclic phosphate (APPR>P). May function as an ADP-ribosylase (By similarity). |
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