Aminoacyl tRNA synthetase 3D structures: Difference between revisions
Michal Harel (talk | contribs) No edit summary |
Michal Harel (talk | contribs) No edit summary |
||
Line 61: | Line 61: | ||
* ''Gln-RS ternary complex'' | * ''Gln-RS ternary complex'' | ||
**[[1euq]], [[1euy]] – EcGlnRS + Gln-tRNA + Gln-SA<br /> | **[[1euq]], [[1euy]] – EcGlnRS + Gln-tRNA + Gln-SA<br /> | ||
**[[1exd]] - EcGlnRS + Gln-tRNA (mutant) + AMP<br /> | **[[1exd]] - EcGlnRS + Gln-tRNA (mutant) + AMP<br /> | ||
Line 83: | Line 84: | ||
* ''Glu-RS + small substrates or analogs'' | * ''Glu-RS + small substrates or analogs'' | ||
**[[3afh]] - TmGluRS + Glu-AMP analog<br /> | **[[3afh]] - TmGluRS + Glu-AMP analog<br /> | ||
**[[2rd2]], [[2re8]] – EcGluRS (mutant) + Glu-SA<br /> | **[[2rd2]], [[2re8]] – EcGluRS (mutant) + Glu-SA<br /> | ||
Line 94: | Line 96: | ||
* ''Glu-RS + tRNA'' | * ''Glu-RS + tRNA'' | ||
**[[1zjw]] – EcGluRS + Glu-tRNA<br /> | **[[1zjw]] – EcGluRS + Glu-tRNA<br /> | ||
**[[1g59]] – TtGluRS + Glu-tRNA<br /> | **[[1g59]] – TtGluRS + Glu-tRNA<br /> | ||
* ''Glu-RS ternary complex'' | * ''Glu-RS ternary complex'' | ||
**[[5bmu]] – hGluRS GST-like domain + EPRS-AIMP3 <br /> | **[[5bmu]] – hGluRS GST-like domain + EPRS-AIMP3 <br /> | ||
**[[2hrk]], [[2hsm]] - yGluRS N-terminal + GU4 nucleic-binding protein 1<br /> | **[[2hrk]], [[2hsm]] - yGluRS N-terminal + GU4 nucleic-binding protein 1<br /> | ||
Line 113: | Line 117: | ||
* ''Ile-RS + small substrates or analogs'' | * ''Ile-RS + small substrates or analogs'' | ||
**[[1ue0]] - TtIleRS editing domain + Val<br /> | **[[1ue0]] - TtIleRS editing domain + Val<br /> | ||
**[[1wnz]] - TtIleS editing domain + Val-adenylate<br /> | **[[1wnz]] - TtIleS editing domain + Val-adenylate<br /> | ||
Line 120: | Line 125: | ||
* ''Ile-RS ternary complex'' | * ''Ile-RS ternary complex'' | ||
**[[1ffy]], [[1qu2]], [[1qu3]] - SaIleRS + Ile-tRNA + antibiotic - ''Staphylococcus aureus''<br /> | **[[1ffy]], [[1qu2]], [[1qu3]] - SaIleRS + Ile-tRNA + antibiotic - ''Staphylococcus aureus''<br /> | ||
**[[6ldk]] - CaIleRS + AMP + Ile – ''Candida albicans''<br /> | **[[6ldk]] - CaIleRS + AMP + Ile – ''Candida albicans''<br /> | ||
Line 143: | Line 149: | ||
* ''Leu-RS + small substrates or analogs'' | * ''Leu-RS + small substrates or analogs'' | ||
**[[6kqy]] - hLeuRS + Leu<br /> | **[[6kqy]] - hLeuRS + Leu<br /> | ||
**[[7d5c]] - yLeuRS + inhibitor<br /> | **[[7d5c]] - yLeuRS + inhibitor<br /> | ||
Line 170: | Line 177: | ||
* ''Leu-RS + tRNA'' | * ''Leu-RS + tRNA'' | ||
**[[1wz2]] – PhLeuRS + Leu-tRNA<br /> | **[[1wz2]] – PhLeuRS + Leu-tRNA<br /> | ||
**[[5ah5]] - LeuRS + Leu-tRNA – ''Agrobacterium radiobacter''<br > | **[[5ah5]] - LeuRS + Leu-tRNA – ''Agrobacterium radiobacter''<br > | ||
* ''Leu-RS ternary complex'' | * ''Leu-RS ternary complex'' | ||
**[[6kie]], [[6kr7]] - hLeuRS + Leu-SA + Leu<br /> | **[[6kie]], [[6kr7]] - hLeuRS + Leu-SA + Leu<br /> | ||
**[[6lpf]], [[6lr6]] - hLeuRS + Leu-SA + adenosine derivative<br /> | **[[6lpf]], [[6lr6]] - hLeuRS + Leu-SA + adenosine derivative<br /> | ||
Line 256: | Line 265: | ||
* ''Met-RS + small substrates or analogs'' | * ''Met-RS + small substrates or analogs'' | ||
**[[5goy]] – hMetRS residues 221-834 + Met<br /> | **[[5goy]] – hMetRS residues 221-834 + Met<br /> | ||
**[[3kfl]] – LmMetRS residues 206-747+ Met-adenylate - ''Leishmania major''<br /> | **[[3kfl]] – LmMetRS residues 206-747+ Met-adenylate - ''Leishmania major''<br /> | ||
Line 485: | Line 495: | ||
* ''Asp-RS + small substrates or analogs'' | * ''Asp-RS + small substrates or analogs'' | ||
**[[3nel]] – TkAspRS + Asp<br /> | **[[3nel]] – TkAspRS + Asp<br /> | ||
**[[3nem]] - TkAspRS + Asp-adenylate<br /> | **[[3nem]] - TkAspRS + Asp-adenylate<br /> | ||
Line 674: | Line 685: | ||
**[[5vad]] – hGlu/ProRS residues 1003-1513 + inhibitor<br /> | **[[5vad]] – hGlu/ProRS residues 1003-1513 + inhibitor<br /> | ||
**[[7osy]] – hGlu/ProRS residues 1003-1513 + Pro<br /> | **[[7osy]] – hGlu/ProRS residues 1003-1513 + Pro<br /> | ||
**[[7bbu]], [[7f98]], [[7f99]], [[7f9a]], | **[[7bbu]], [[7f98]], [[7f99]], [[7f9a]], [[7f9b]], [[7f9c]], [[7f9d]], [[7osz]], [[7ot0]], [[7ot1]], [[7ot2]], [[7ot3]] – hGlu/ProRS residues 1003-1513 + inhibitor + Pro<br /> | ||
**[[7x09]], [[7x1o]] – hGlu/ProRS residues 1003-1513 + inhibitor + halofuginone<br /> | **[[7x09]], [[7x1o]] – hGlu/ProRS residues 1003-1513 + inhibitor + halofuginone<br /> | ||
**[[7y1w]], [[7y28]], [[7y3s]] – hGlu/ProRS residues 1003-1513 + inhibitor + ATP<br /> | **[[7y1w]], [[7y28]], [[7y3s]] – hGlu/ProRS residues 1003-1513 + inhibitor + ATP<br /> | ||
**[[5a1n]], [[5a34]], [[5a5h]] – hGlu/ProRS GST-like domain + EPRS-AIMP2<br /> | **[[5a1n]], [[5a34]], [[5a5h]] – hGlu/ProRS GST-like domain 1-175 + EPRS-AIMP2<br /> | ||
**[[1fyj]] – hGlu/ProRS 677-733 – NMR<br /> | **[[1fyj]] – hGlu/ProRS 677-733 – NMR<br /> | ||