9az4: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
The entry | ==INF2 at the Barbed End of F-Actin== | ||
<StructureSection load='9az4' size='340' side='right'caption='[[9az4]], [[Resolution|resolution]] 3.37Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9az4]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9AZ4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9AZ4 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.37Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=HIC:4-METHYL-HISTIDINE'>HIC</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9az4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9az4 OCA], [https://pdbe.org/9az4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9az4 RCSB], [https://www.ebi.ac.uk/pdbsum/9az4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9az4 ProSAT]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[https://www.uniprot.org/uniprot/INF2_HUMAN INF2_HUMAN] Autosomal dominant intermediate Charcot-Marie-Tooth disease type E;Genetic steroid-resistant nephrotic syndrome. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/INF2_HUMAN INF2_HUMAN] Severs actin filaments and accelerates their polymerization and depolymerization. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Oryctolagus cuniculus]] | |||
[[Category: Barrie KR]] | |||
[[Category: Dominguez R]] | |||
[[Category: Palmer NJ]] | |||
Latest revision as of 21:10, 29 May 2024
INF2 at the Barbed End of F-ActinINF2 at the Barbed End of F-Actin
Structural highlights
DiseaseINF2_HUMAN Autosomal dominant intermediate Charcot-Marie-Tooth disease type E;Genetic steroid-resistant nephrotic syndrome. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. FunctionINF2_HUMAN Severs actin filaments and accelerates their polymerization and depolymerization. |
| ||||||||||||||||||