8sze: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[8sze]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Yersinia_pestis Yersinia pestis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8SZE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8SZE FirstGlance]. <br> | <table><tr><td colspan='2'>[[8sze]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Yersinia_pestis Yersinia pestis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8SZE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8SZE FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TOP:TRIMETHOPRIM'>TOP</scene></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TOP:TRIMETHOPRIM'>TOP</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8sze FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8sze OCA], [https://pdbe.org/8sze PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8sze RCSB], [https://www.ebi.ac.uk/pdbsum/8sze PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8sze ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8sze FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8sze OCA], [https://pdbe.org/8sze PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8sze RCSB], [https://www.ebi.ac.uk/pdbsum/8sze PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8sze ProSAT]</span></td></tr> | ||
</table> | </table> | ||
Latest revision as of 13:54, 22 May 2024
Crystal structure of Yersinia pestis dihydrofolate reductase in complex with TrimethoprimCrystal structure of Yersinia pestis dihydrofolate reductase in complex with Trimethoprim
Structural highlights
FunctionA0A3N4BLI0_YERPE Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.[ARBA:ARBA00025067][PIRNR:PIRNR000194] |
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