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==Cytoplasmic dynein-1 heavy chain bound to JIP3-RH1== | |||
<StructureSection load='8pr3' size='340' side='right'caption='[[8pr3]], [[Resolution|resolution]] 3.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8pr3]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8PR3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8PR3 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.9Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8pr3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8pr3 OCA], [https://pdbe.org/8pr3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8pr3 RCSB], [https://www.ebi.ac.uk/pdbsum/8pr3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8pr3 ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/JIP3_HUMAN JIP3_HUMAN] The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins (By similarity). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Carter AP]] | |||
[[Category: Gassmann R]] | |||
[[Category: Lau CK]] | |||
[[Category: Manigrasso G]] | |||
[[Category: Singh K]] | |||
Latest revision as of 13:11, 27 March 2024
Cytoplasmic dynein-1 heavy chain bound to JIP3-RH1Cytoplasmic dynein-1 heavy chain bound to JIP3-RH1
Structural highlights
FunctionJIP3_HUMAN The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins (By similarity). |
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