8pr3
Cytoplasmic dynein-1 heavy chain bound to JIP3-RH1Cytoplasmic dynein-1 heavy chain bound to JIP3-RH1
Structural highlights
FunctionJIP3_HUMAN The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins (By similarity). |
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