1ef5: Difference between revisions

← Older edit Newer edit →

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
 ==SOLUTION STRUCTURE OF THE RAS-BINDING DOMAIN OF RGL==
-<StructureSection load='1ef5' size='340' side='right'caption='[[1ef5]], [[NMR_Ensembles_of_Models | 1 NMR models]]' scene=''>
+<StructureSection load='1ef5' size='340' side='right'caption='[[1ef5]]' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1ef5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EF5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EF5 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1ef5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EF5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EF5 FirstGlance]. <br>
-</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ef5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ef5 OCA], [https://pdbe.org/1ef5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ef5 RCSB], [https://www.ebi.ac.uk/pdbsum/1ef5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ef5 ProSAT], [https://www.topsan.org/Proteins/RSGI/1ef5 TOPSAN]</span></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ef5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ef5 OCA], [https://pdbe.org/1ef5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ef5 RCSB], [https://www.ebi.ac.uk/pdbsum/1ef5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ef5 ProSAT], [https://www.topsan.org/Proteins/RSGI/1ef5 TOPSAN]</span></td></tr>
 </table>
 == Function ==
-[[https://www.uniprot.org/uniprot/RGL1_MOUSE RGL1_MOUSE]] Probable guanine nucleotide exchange factor.
+[https://www.uniprot.org/uniprot/RGL1_MOUSE RGL1_MOUSE] Probable guanine nucleotide exchange factor.
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
@@ Line 18: / Line 19: @@
 </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ef5 ConSurf].
 <div style="clear:both"></div>
-<div style="background-color:#fffaf0;">
-== Publication Abstract from PubMed ==
-The RGL protein, a homolog of the Ral GDP dissociation stimulator (RalGDS), has been identified as a downstream effector of Ras. In the present study, the solution structure of the Ras-binding domain of RGL (RGL-RBD) was determined by NMR spectroscopy. The overall fold of RGL-RBD consists of a five-stranded beta-sheet and two alpha-helices, which is the same topology as that of RalGDS-RBD. The backbone chemical shift perturbation of RGL-RBD upon interaction with the GTP analog-bound Ras was also examined. The solution structure of RGL-RBD, especially around some of the Ras-interacting residues, is appreciably different from that of RalGDS-RBD.
-Solution structure of the Ras-binding domain of RGL.,Kigawa T, Endo M, Ito Y, Shirouzu M, Kikuchi A, Yokoyama S FEBS Lett. 1998 Dec 28;441(3):413-8. PMID:9891982<ref>PMID:9891982</ref>
-From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-</div>
-<div class="pdbe-citations 1ef5" style="background-color:#fffaf0;"></div>
-== References ==
-<references/>
 __TOC__
 </StructureSection>
 [[Category: Large Structures]]
-[[Category: Lk3 transgenic mice]]
+[[Category: Mus musculus]]
-[[Category: Endo, M]]
+[[Category: Endo M]]
-[[Category: Ito, Y]]
+[[Category: Ito Y]]
-[[Category: Kigawa, T]]
+[[Category: Kigawa T]]
-[[Category: Kikuchi, A]]
+[[Category: Kikuchi A]]
-[[Category: Structural genomic]]
+[[Category: Shirouzu M]]
-[[Category: Shirouzu, M]]
+[[Category: Yokoyama S]]
-[[Category: Yokoyama, S]]
-[[Category: Ra]]
-[[Category: Ras-binding domain]]
-[[Category: Rbd]]
-[[Category: Rgl]]
-[[Category: Rsgi]]
-[[Category: Signaling protein]]