6wj3: Difference between revisions

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-====
+==CryoEM structure of the SLC38A9-RagA-RagC-Ragulator complex in the post-GAP state==
-<StructureSection load='6wj3' size='340' side='right'caption='[[6wj3]]' scene=''>
+<StructureSection load='6wj3' size='340' side='right'caption='[[6wj3]], [[Resolution|resolution]] 3.90&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
+<table><tr><td colspan='2'>[[6wj3]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WJ3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6WJ3 FirstGlance]. <br>
-</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6wj3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wj3 OCA], [http://pdbe.org/6wj3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6wj3 RCSB], [http://www.ebi.ac.uk/pdbsum/6wj3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6wj3 ProSAT]</span></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.9&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=U3J:xanthosine+diphosphate'>U3J</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6wj3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wj3 OCA], [https://pdbe.org/6wj3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6wj3 RCSB], [https://www.ebi.ac.uk/pdbsum/6wj3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6wj3 ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/RRAGC_HUMAN RRAGC_HUMAN] Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids.<ref>PMID:20381137</ref>
+==See Also==
+*[[GTP-binding protein 3D structures|GTP-binding protein 3D structures]]
+*[[Ragulator complex 3D structures|Ragulator complex 3D structures]]
+== References ==
+<references/>
 __TOC__
 </StructureSection>
+[[Category: Homo sapiens]]
 [[Category: Large Structures]]
-[[Category: Z-disk]]
+[[Category: Fromm SA]]
+[[Category: Hurley JH]]