4akd: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| Line 4: | Line 4: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4akd]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Artocarpus_integer Artocarpus integer]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AKD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AKD FirstGlance]. <br> | <table><tr><td colspan='2'>[[4akd]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Artocarpus_integer Artocarpus integer]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AKD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AKD FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4akd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4akd OCA], [https://pdbe.org/4akd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4akd RCSB], [https://www.ebi.ac.uk/pdbsum/4akd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4akd ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4akd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4akd OCA], [https://pdbe.org/4akd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4akd RCSB], [https://www.ebi.ac.uk/pdbsum/4akd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4akd ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/Q7M1T4_ARTIN Q7M1T4_ARTIN] | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 26: | Line 28: | ||
[[Category: Artocarpus integer]] | [[Category: Artocarpus integer]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Abdul-Rahman | [[Category: Abdul-Rahman PS]] | ||
[[Category: Cogdell | [[Category: Cogdell RJ]] | ||
[[Category: Gabrielsen | [[Category: Gabrielsen M]] | ||
[[Category: Hashim | [[Category: Hashim OH]] | ||
[[Category: Othman | [[Category: Othman S]] | ||
Latest revision as of 14:29, 20 December 2023
High resolution structure of Mannose Binding lectin from Champedak (CMB)High resolution structure of Mannose Binding lectin from Champedak (CMB)
Structural highlights
FunctionPublication Abstract from PubMedGalactose-binding and mannose-binding lectins from the champedak fruit, which is native to South-east Asia, exhibit useful potential clinical applications. The specificity of the two lectins for their respective ligands allows the detection of potential cancer biomarkers and monitoring of the glycosylated state of proteins in human serum and/or urine. To fully understand and expand the use of these natural proteins, their complete sequences and crystal structures are presented here, together with details of sugar binding. Structures and binding specificity of galactose- and mannose-binding lectins from champedak: differences from jackfruit lectins.,Gabrielsen M, Abdul-Rahman PS, Othman S, Hashim OH, Cogdell RJ Acta Crystallogr F Struct Biol Commun. 2014 Jun;70(Pt 6):709-16. doi:, 10.1107/S2053230X14008966. Epub 2014 May 24. PMID:24915077[1] From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. See AlsoReferences
|
| ||||||||||||||||||