8sx2: Difference between revisions

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'''Unreleased structure'''


The entry 8sx2 is ON HOLD  until Paper Publication
==PARP4 catalytic domain bound to EB47==
 
<StructureSection load='8sx2' size='340' side='right'caption='[[8sx2]], [[Resolution|resolution]] 2.95&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8sx2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8SX2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8SX2 FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.95&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UHB:2-[4-[(2S,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-BIS(OXIDANYL)OXOLAN-2-YL]CARBONYLPIPERAZIN-1-YL]-N-(1-OXIDANYLIDENE-2,3-DIHYDROISOINDOL-4-YL)ETHANAMIDE'>UHB</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8sx2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8sx2 OCA], [https://pdbe.org/8sx2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8sx2 RCSB], [https://www.ebi.ac.uk/pdbsum/8sx2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8sx2 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PARP4_HUMAN PARP4_HUMAN] Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins.<ref>PMID:25043379</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Frigon L]]
[[Category: Pascal JM]]

Latest revision as of 15:06, 8 November 2023

PARP4 catalytic domain bound to EB47PARP4 catalytic domain bound to EB47

Structural highlights

8sx2 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.95Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PARP4_HUMAN Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins.[1]

References

  1. ↑ Vyas S, Matic I, Uchima L, Rood J, Zaja R, Hay RT, Ahel I, Chang P. Family-wide analysis of poly(ADP-ribose) polymerase activity. Nat Commun. 2014 Jul 21;5:4426. PMID:25043379 doi:10.1038/ncomms5426

8sx2, resolution 2.95Å

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OCA
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