Proteopedia

8sx2

PARP4 catalytic domain bound to EB47PARP4 catalytic domain bound to EB47

Structural highlights

8sx2 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.95Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PARP4_HUMAN Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins.[1]

References

  1. ↑ Vyas S, Matic I, Uchima L, Rood J, Zaja R, Hay RT, Ahel I, Chang P. Family-wide analysis of poly(ADP-ribose) polymerase activity. Nat Commun. 2014 Jul 21;5:4426. PMID:25043379 doi:10.1038/ncomms5426

8sx2, resolution 2.95Å

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OCA
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