8ajr: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[8ajr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8AJR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8AJR FirstGlance]. <br> | <table><tr><td colspan='2'>[[8ajr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8AJR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8AJR FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ajr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ajr OCA], [https://pdbe.org/8ajr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ajr RCSB], [https://www.ebi.ac.uk/pdbsum/8ajr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ajr ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ajr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ajr OCA], [https://pdbe.org/8ajr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ajr RCSB], [https://www.ebi.ac.uk/pdbsum/8ajr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ajr ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/A0A8C5LDB3_JACJA A0A8C5LDB3_JACJA] Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).[PIRNR:PIRNR038006] | [https://www.uniprot.org/uniprot/A0A8C5LDB3_JACJA A0A8C5LDB3_JACJA] Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).[PIRNR:PIRNR038006] | ||
==See Also== | |||
*[[Methyl CpG binding protein 3D structures|Methyl CpG binding protein 3D structures]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 09:19, 19 July 2023
The Solution Structure of the Triple Mutant Methyl-CpG-Binding Domain from MeCP2The Solution Structure of the Triple Mutant Methyl-CpG-Binding Domain from MeCP2
Structural highlights
FunctionA0A8C5LDB3_JACJA Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).[PIRNR:PIRNR038006] See Also |
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