Kelch-like protein 3D structures

3D Structures of Kelch-like protein3D Structures of Kelch-like protein

Updated on 13-June-2023

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• Kelch-like protein 2
  • 2xn4 – hKLHL2 Kelch domain - human
    
• Kelch-like protein 3
  • 4chb, 4ch9, 5nkp – hKLHL3 Kelch domain + serine/threonine protein kinas WNK4 peptide
    
  • 4hxi – hKLHL3 BTB-BACK domain (mutant) + cullin-3 N terminal
    
• Kelch-like protein 4
  • 2eqx – hKLHL4 BACK domain - NMR
    
• Kelch-like protein 5
  • 4asc – hKLHL5 Kelch domain
    
• Kelch-like protein 7
  • 3ii7 – hKLHL7 Kelch domain
    
• Kelch-like protein 10
  • 2woz – KLHL10 Kelch domain - rat
    
• Kelch-like protein 11
  • 3i3n – hKLHL11 BTB-BACK domain
    
  • 4ap2, 4apf – hKLHL11 BTB-BACK domain + cullin-3 N terminal
    
• Kelch-like protein 12
  • 2vpj – hKLHL12 Kelch domain
    
  • 6ttk, 6v7o – hKLHL12 Kelch domain + peptide
    
• Kelch-like protein 16 (gigaxonin)
  • 3hve – hKLHL16
    
  • 2ppi – hKLHL16 BTB domain
    
• Kelch-like protein 17 (actinfilin)
  • 6hrl – hKLHL17
    
• Kelch-like protein 19 (kelch-like ECH-associated protein 1; Keap1)); domains: BTB 48-140; kelch 320-812
  • 1u6d, 1zgk, 4ifj, 6rog, 7xot – hKeap1 Kelch domain
    
  • 3zgd, 5wfl, 6w67, 6w68, 6w69 – hKeap1 Kelch domain (mutant)
    
  • 4cxi, 4cxj, 6w68, 6w69, 7exi – hKeap1 BTB domain (mutant)
    
  • 1x2j – mKeap1 Kelch domain
    
• Keap1 complex with peptide
  • 4ifl, 2flu, 3zgc, 7k28, 7k29, 7k2a, 7k2b, 7k2c, 7k2d, 7k2e, 7k2f, 7k2i, 7k2j, 7k2l, 7k2m, 7k2g, 7k2h 7k2k, 7k2n, 7k2o 7k2p, 7k2q 7k2r, 7k2s – hKeap1 Kelch domain + NRF2 Neh2 peptide
    
  • 5wfv, 5wg1 – hKeap1 Kelch domain (mutant) + NRF2 peptide
    
  • 6fmp, 6fmq, 6t7v, 6t7z, 6tg8 – hKeap1 Kelch domain + peptide
    
  • 5f72 – hKeap1 Kelch domain + antibody
    
  • 5x54 – hKeap1 Kelch domain + tetrapeptide
    
  • 5nlb – hKLHL1 BTB+ 3-BOX domains + CUL-3
    
  • 4xmb – hKLHL1 Kelch domain + NRF2 activator
    
  • 5cgj – mKLHL1 Kelch domain + NRF2 activator - mouse
    
  • 1x2r – mKeap1 Kelch domain + NRF2 Neh2 peptide
    
  • 2z32 – mKeap1 Kelch domain + prothymosin a peptide
    
  • 3ade, 3wdz – mKeap1 Kelch domain + sequestosome-1 peptide
    
  • 2dyh – mKeap1 Kelch domain + NRF2 residues 22-36
    
  • 3wn7 – mKeap1 Kelch domain + NRF2 residues 17-51
    
• Keap1 complex with small molecule
  • 3vng, 3vnh, 6ffm – hKeap1 Kelch domain + oxadiazole derivative
    
  • 6z6a, 7q5h, 7q6q, 7q6x, 7q8r, 7q96 – hKeap1 Kelch domain + macrocycle
    
  • 4ifn, 6tym, 6typ, 6v6z – hKeap1 Kelch domain + quinoline derivative
    
  • 4l7b, 4l7c, 4l7d 4n1b, 6uf0 – hKeap1 Kelch domain (mutant) + quinoline derivative
    
  • 4zy3, 5fnq, 5fnr, 5fns, 5fnt, 5fnu, 5fzj, 5fzn, 4in4, 6hws, 6sp1, 6sp4, 7xm2, 7xm3, 7xm4, 7xm5 – hKeap1 Kelch domain + inhibitor
    
  • 4n1b, 4iqk, 5wiy, 5whl, 5who – hKeap1 Kelch domain (mutant) + inhibitor
    
  • 5dad, 5daf – hKeap1 BTB domain + activator
    
  • 5git, 7x4w, 7x4x – hKeap1 BTB domain + inhibitor
    
  • 4cxt – hKeap1 BTB domain (mutant) + antagonist
    
  • 6qmc, 6qmd, 6qme, 6qmj, 6qmk – mKeap1 Kelch domain + inhibitor
    
  • 7c60 – mKeap1 Kelch domain + fumarate derivative
    
• Keap1 complex with protein
  • 6w66 – hKeap1 BTB domain (mutant) + SKP1 + FBXL17
    
  • 6wcq – hKeap1 BTB domain (mutant) + SKP1 + FBXL17 + cullin-1 – Cryo EM
    
• Kelch-like protein 20
  • 5yq4 – hKLHL20 kelch domain
    
  • 6gy5 – hKLHL20 kelch domain + DAPK1 peptide
    
  • 8cia – hKLHL20 kelch domain + kelch like family member 20