8bpf: Difference between revisions

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-'''Unreleased structure'''
-The entry 8bpf is ON HOLD  until Paper Publication
+==FcMR binding at subunit Fcu1 of IgM pentamer==
+<StructureSection load='8bpf' size='340' side='right'caption='[[8bpf]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8bpf]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8BPF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8BPF FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8bpf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8bpf OCA], [https://pdbe.org/8bpf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8bpf RCSB], [https://www.ebi.ac.uk/pdbsum/8bpf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8bpf ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/FAIM3_HUMAN FAIM3_HUMAN] May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.<ref>PMID:9586636</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Chen Q]]
+[[Category: Rosenthal P]]
+[[Category: Tolar P]]