2m6o: Difference between revisions

No edit summary
No edit summary
Line 1: Line 1:


==The actinobacterial transcription factor RbpA binds to the principal sigma subunit of RNA polymerase==
==The actinobacterial transcription factor RbpA binds to the principal sigma subunit of RNA polymerase==
<StructureSection load='2m6o' size='340' side='right'caption='[[2m6o]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
<StructureSection load='2m6o' size='340' side='right'caption='[[2m6o]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2m6o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Strco Strco]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M6O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M6O FirstGlance]. <br>
<table><tr><td colspan='2'>[[2m6o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_coelicolor_A3(2) Streptomyces coelicolor A3(2)]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M6O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M6O FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2m6p|2m6p]]</div></td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m6o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m6o OCA], [https://pdbe.org/2m6o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m6o RCSB], [https://www.ebi.ac.uk/pdbsum/2m6o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m6o ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SCO1421 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=100226 STRCO])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m6o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m6o OCA], [https://pdbe.org/2m6o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m6o RCSB], [https://www.ebi.ac.uk/pdbsum/2m6o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m6o ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RBPA_STRCO RBPA_STRCO] Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Stimulates transcription from several principal sigma factor HrdB (SigA)-dependent promoters but not from a SigR-dependent promoter. Stimulation occurs in the presence of the transcription initiation inhibitor rifampicin (Rif).[HAMAP-Rule:MF_01483]<ref>PMID:16629670</ref> <ref>PMID:23605043</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 22: Line 22:
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Strco]]
[[Category: Doughty P]]
[[Category: Doughty, P]]
[[Category: Ghosh S]]
[[Category: Ghosh, S]]
[[Category: Lewis R]]
[[Category: Lewis, R]]
[[Category: Liu B]]
[[Category: Liu, B]]
[[Category: Matthews S]]
[[Category: Matthews, S]]
[[Category: Paget M]]
[[Category: Paget, M]]
[[Category: Parsy M]]
[[Category: Parsy, M]]
[[Category: Simpson P]]
[[Category: Simpson, P]]
[[Category: Tabib-Salazar A]]
[[Category: Tabib-Salazar, A]]
[[Category: Rbpa]]
[[Category: Rnap]]
[[Category: Sigma factor]]
[[Category: Transcription]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA