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==== | ==cryo-EM structures of a synaptobrevin-Munc18-1-syntaxin-1 complex class1== | ||
<StructureSection load='7udc' size='340' side='right'caption='[[7udc]]' scene=''> | <StructureSection load='7udc' size='340' side='right'caption='[[7udc]], [[Resolution|resolution]] 3.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | <table><tr><td colspan='2'>[[7udc]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7UDC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7UDC FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7udc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7udc OCA], [https://pdbe.org/7udc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7udc RCSB], [https://www.ebi.ac.uk/pdbsum/7udc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7udc ProSAT]</span></td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7udc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7udc OCA], [https://pdbe.org/7udc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7udc RCSB], [https://www.ebi.ac.uk/pdbsum/7udc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7udc ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[[https://www.uniprot.org/uniprot/STXB1_RAT STXB1_RAT]] May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions. | |||
==See Also== | |||
*[[Syntaxin 3D structures|Syntaxin 3D structures]] | |||
*[[Syntaxin-binding protein|Syntaxin-binding protein]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Rattus norvegicus]] | ||
[[Category: Bai X]] | |||
[[Category: Rizo J]] | |||
[[Category: Stepien KP]] | |||
[[Category: Xu J]] | |||
[[Category: Zhang X]] | |||
Revision as of 10:23, 8 September 2022
cryo-EM structures of a synaptobrevin-Munc18-1-syntaxin-1 complex class1cryo-EM structures of a synaptobrevin-Munc18-1-syntaxin-1 complex class1
Structural highlights
Function[STXB1_RAT] May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions. See Also |
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