1hns: Difference between revisions
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'''H-NS (DNA-BINDING DOMAIN)''' | '''H-NS (DNA-BINDING DOMAIN)''' | ||
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[[Category: Shindo, H.]] | [[Category: Shindo, H.]] | ||
[[Category: Ueguchi, C.]] | [[Category: Ueguchi, C.]] | ||
[[Category: | [[Category: Histone-like protein h1]] | ||
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Revision as of 19:02, 2 May 2008
H-NS (DNA-BINDING DOMAIN)
OverviewOverview
The three-dimensional structure of the C-terminal domain (47 residues) obtained from the hydrolysis of H-NS protein with bovine trypsin was determined by NMR measurements and distance geometry calculations. It is composed of an antiparallel beta-sheet, an alpha-helix and a 3(10)-helix which form a hydrophobic core, stabilizing the whole structure. This domain has been found to bind to DNA. Possible DNA binding sites are discussed on the basis of the solution structure of the C-terminal domain of H-NS.
About this StructureAbout this Structure
1HNS is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.
ReferenceReference
Solution structure of the DNA binding domain of a nucleoid-associated protein, H-NS, from Escherichia coli., Shindo H, Iwaki T, Ieda R, Kurumizaka H, Ueguchi C, Mizuno T, Morikawa S, Nakamura H, Kuboniwa H, FEBS Lett. 1995 Feb 27;360(2):125-31. PMID:7875316 Page seeded by OCA on Fri May 2 19:02:55 2008