Intracrine signaling: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
No edit summary
No edit summary
 
Line 1: Line 1:
<StructureSection load='1bwx' size='340' side='right' caption='Human parathyroid hormone fragment hPTH (1-39); [[1bwx]]' scene=''>
<StructureSection load='1bwx' size='340' side='right' caption='Human parathyroid hormone fragment hPTH (1-39); [[1bwx]]' scene=''>
Intracrine refers to a hormone that acts inside a cell, regulating intracellular events. In simple terms it means that the cell stimulates itself by cellular production of a factor that acts within the cell. Steroid hormones act through intracellular (mostly nuclear) receptors and, thus, may be considered to be intracrines.
Intracrine refers to a hormone that acts inside a cell, regulating intracellular events. In simple terms it means that the cell stimulates itself by cellular production of a factor that acts within the cell. [[Steroid hormones]] act through intracellular (mostly nuclear) receptors and, thus, may be considered to be intracrines.
*[[Intracellular receptors]]
*[[Intracellular receptors]]
*[[Nuclear receptors]]
*[[Nuclear receptors]]

Latest revision as of 14:37, 27 April 2022

Intracrine refers to a hormone that acts inside a cell, regulating intracellular events. In simple terms it means that the cell stimulates itself by cellular production of a factor that acts within the cell. Steroid hormones act through intracellular (mostly nuclear) receptors and, thus, may be considered to be intracrines.

There are several protein/peptide hormones that are also intracrines. Notable examples that have been described in the references include:

  • Peptides of the renin–angiotensin system: angiotensin II and angiotensin (1-7)
  • Fibroblast growth factor 2
  • Parathyroid hormone-related protein

See also Signal transduction.

Human parathyroid hormone fragment hPTH (1-39); 1bwx

Drag the structure with the mouse to rotate

ReferencesReferences

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky