Intracrine signaling

Intracrine refers to a hormone that acts inside a cell, regulating intracellular events. In simple terms it means that the cell stimulates itself by cellular production of a factor that acts within the cell. Steroid hormones act through intracellular (mostly nuclear) receptors and, thus, may be considered to be intracrines. Intracellular receptors Nuclear receptors There are several protein/peptide hormones that are also intracrines. Notable examples that have been described in the references include: Peptides of the renin–angiotensin system: angiotensin II and angiotensin (1-7) Fibroblast growth factor 2 Parathyroid hormone-related protein See also Signal transduction.

spinqualitylabelsall models Human parathyroid hormone fragment hPTH (1-39); 1bwx Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image