2dk4: Difference between revisions

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<StructureSection load='2dk4' size='340' side='right'caption='[[2dk4]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2dk4' size='340' side='right'caption='[[2dk4]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2dk4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DK4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DK4 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2dk4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DK4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DK4 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PRPF18, HPRP18 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PRPF18, HPRP18 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dk4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dk4 OCA], [http://pdbe.org/2dk4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dk4 RCSB], [http://www.ebi.ac.uk/pdbsum/2dk4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2dk4 ProSAT], [http://www.topsan.org/Proteins/RSGI/2dk4 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dk4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dk4 OCA], [https://pdbe.org/2dk4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dk4 RCSB], [https://www.ebi.ac.uk/pdbsum/2dk4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dk4 ProSAT], [https://www.topsan.org/Proteins/RSGI/2dk4 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PRP18_HUMAN PRP18_HUMAN]] Participates in the second step of pre-mRNA splicing.<ref>PMID:9000057</ref>   
[[https://www.uniprot.org/uniprot/PRP18_HUMAN PRP18_HUMAN]] Participates in the second step of pre-mRNA splicing.<ref>PMID:9000057</ref>   
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 23:38, 20 October 2021

Solution structure of Splicing Factor Motif in Pre-mRNA splicing factor 18 (hPRP18)Solution structure of Splicing Factor Motif in Pre-mRNA splicing factor 18 (hPRP18)

Structural highlights

2dk4 is a 1 chain structure with sequence from Human. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Gene:PRPF18, HPRP18 (HUMAN)
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

[PRP18_HUMAN] Participates in the second step of pre-mRNA splicing.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. ↑ Horowitz DS, Krainer AR. A human protein required for the second step of pre-mRNA splicing is functionally related to a yeast splicing factor. Genes Dev. 1997 Jan 1;11(1):139-51. PMID:9000057
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OCA
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