Proteopedia

2dk4

Solution structure of Splicing Factor Motif in Pre-mRNA splicing factor 18 (hPRP18)Solution structure of Splicing Factor Motif in Pre-mRNA splicing factor 18 (hPRP18)

Structural highlights

2dk4 is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

PRP18_HUMAN Participates in the second step of pre-mRNA splicing.[1]

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. ↑ Horowitz DS, Krainer AR. A human protein required for the second step of pre-mRNA splicing is functionally related to a yeast splicing factor. Genes Dev. 1997 Jan 1;11(1):139-51. PMID:9000057
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OCA
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