4rw1: Difference between revisions
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==Hen egg-white lysozyme structure from a spent-beam experiment at LCLS: original beam== | ==Hen egg-white lysozyme structure from a spent-beam experiment at LCLS: original beam== | ||
<StructureSection load='4rw1' size='340' side='right' caption='[[4rw1]], [[Resolution|resolution]] 1.90Å' scene=''> | <StructureSection load='4rw1' size='340' side='right'caption='[[4rw1]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4rw1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RW1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RW1 FirstGlance]. <br> | <table><tr><td colspan='2'>[[4rw1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RW1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RW1 FirstGlance]. <br> | ||
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</div> | </div> | ||
<div class="pdbe-citations 4rw1" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 4rw1" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Lysozyme 3D structures|Lysozyme 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Gallus gallus]] | [[Category: Gallus gallus]] | ||
[[Category: Large Structures]] | |||
[[Category: Lysozyme]] | [[Category: Lysozyme]] | ||
[[Category: Botha, S]] | [[Category: Botha, S]] | ||
Revision as of 11:10, 19 February 2020
Hen egg-white lysozyme structure from a spent-beam experiment at LCLS: original beamHen egg-white lysozyme structure from a spent-beam experiment at LCLS: original beam
Structural highlights
Function[LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.[1] Publication Abstract from PubMedX-ray free-electron laser sources such as the Linac Coherent Light Source offer very exciting possibilities for unique research. However, beam time at such facilities is very limited and in high demand. This has led to significant efforts towards beam multiplexing of various forms. One such effort involves re-using the so-called spent beam that passes through the hole in an area detector after a weak interaction with a primary sample. This beam can be refocused into a secondary interaction region and used for a second, independent experiment operating in series. The beam profile of this refocused beam was characterized for a particular experimental geometry at the Coherent X-ray Imaging instrument at LCLS. A demonstration of this multiplexing capability was performed with two simultaneous serial femtosecond crystallography experiments, both yielding interpretable data of sufficient quality to produce electron density maps. Characterization and use of the spent beam for serial operation of LCLS.,Boutet S, Foucar L, Barends TR, Botha S, Doak RB, Koglin JE, Messerschmidt M, Nass K, Schlichting I, Seibert MM, Shoeman RL, Williams GJ J Synchrotron Radiat. 2015 May 1;22(Pt 3):634-43. doi: 10.1107/S1600577515004002., Epub 2015 Apr 11. PMID:25931079[2] From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. See AlsoReferences
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