Deoxycytidine kinase: Difference between revisions
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The ability of <scene name='54/543346/Cv/4'>DCK to phosphorylate multiple nucleosides arises from the different conformations which the active site glutamic acid can assume</scene> (active site glutamates are in yellow).<ref>PMID:12808445</ref> | The ability of <scene name='54/543346/Cv/4'>DCK to phosphorylate multiple nucleosides arises from the different conformations which the active site glutamic acid can assume</scene> (active site glutamates are in yellow).<ref>PMID:12808445</ref> | ||
== 3D Structures of deoxycytidine kinase == | |||
[[Deoxycytidine kinase 3D structures]] | |||
</StructureSection> | </StructureSection> | ||
== 3D Structures of deoxycytidine kinase == | == 3D Structures of deoxycytidine kinase == | ||
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**[[2no9]], [[2noa]], [[2no0]], [[2no6]], [[2zi9]] – hDCK (mutant) + ADP + chemotherapy agent <br /> | **[[2no9]], [[2noa]], [[2no0]], [[2no6]], [[2zi9]] – hDCK (mutant) + ADP + chemotherapy agent <br /> | ||
**[[2zia]], [[4kcg]] – hDCK (mutant) + UDP + chemotherapy agent <br /> | **[[2zia]], [[4kcg]] – hDCK (mutant) + UDP + chemotherapy agent <br /> | ||
**[[5mqi]], [[5mqt]] – hDCK (mutant) + UDP + dCMP + chemotherapy agent<br /> | **[[5mqi]], [[5mqt]], [[5mql]] – hDCK (mutant) + UDP + dCMP + chemotherapy agent<br /> | ||
*dCK complex with nucleoside | *dCK complex with nucleoside | ||