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==Crystal structure of ligand binding domain of CysB, a LysR member from Salmonella typhimurium in complex with effector ligand, O-acetylserine== | ==Crystal structure of ligand binding domain of CysB, a LysR member from Salmonella typhimurium in complex with effector ligand, O-acetylserine== | ||
<StructureSection load='4lq2' size='340' side='right' caption='[[4lq2]], [[Resolution|resolution]] 2.69Å' scene=''> | <StructureSection load='4lq2' size='340' side='right'caption='[[4lq2]], [[Resolution|resolution]] 2.69Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4lq2]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LQ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LQ2 FirstGlance]. <br> | <table><tr><td colspan='2'>[[4lq2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Salty Salty]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LQ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LQ2 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=OAS:O-ACETYLSERINE'>OAS</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=OAS:O-ACETYLSERINE'>OAS</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4gwo|4gwo]], [[4gxa|4gxa]], [[4lon|4lon]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4gwo|4gwo]], [[4gxa|4gxa]], [[4lon|4lon]]</td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cysB, STM1713 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=99287 SALTY])</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lq2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lq2 OCA], [http://pdbe.org/4lq2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4lq2 RCSB], [http://www.ebi.ac.uk/pdbsum/4lq2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4lq2 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lq2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lq2 OCA], [http://pdbe.org/4lq2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4lq2 RCSB], [http://www.ebi.ac.uk/pdbsum/4lq2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4lq2 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Salty]] | |||
[[Category: Kumaran, S]] | [[Category: Kumaran, S]] | ||
[[Category: Mittal, M]] | [[Category: Mittal, M]] |
Revision as of 11:45, 3 April 2019
Crystal structure of ligand binding domain of CysB, a LysR member from Salmonella typhimurium in complex with effector ligand, O-acetylserineCrystal structure of ligand binding domain of CysB, a LysR member from Salmonella typhimurium in complex with effector ligand, O-acetylserine
Structural highlights
Function[CYSB_SALTY] This protein is a positive regulator of gene expression for the cysteine regulon, a system of 10 or more loci involved in the biosynthesis of L-cysteine from inorganic sulfate. The inducer for CysB is N-acetylserine. CysB inhibits its own transcription. See Also |
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