Agglutinin: Difference between revisions

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<StructureSection load='' size='450' side='right' caption='Agglutinin complex with polysaccharide of α- and β-mannose, imidazole and Na+ ion (purple) (PDB code [[4gk9]])' scene='74/749490/Cv/1'>
<StructureSection load='' size='450' side='right' caption='Agglutinin complex with polysaccharide of α- and β-mannose, imidazole and Na+ ion (purple) (PDB code [[4gk9]])' scene='74/749490/Cv/1'>


 
__TOC__
== Function ==
== Function ==
'''Agglutinin'''s or '''galactose-inding lectin''' (AGG) are sugar-binding lectins which cause particles to change from fluid state to thickened-mass state.  '''Agglutinin isolectin''' or '''wheat germ agglutinin''' is a plant protein that binds specifically to sugars expressed by human gastrointestinal epithelial and immune cells<ref>PMID:19332085</ref>.  
'''Agglutinin'''s or '''galactose-inding lectin''' (AGG) are sugar-binding lectins which cause particles to change from fluid state to thickened-mass state.  '''Agglutinin isolectin''' or '''wheat germ agglutinin''' is a plant protein that binds specifically to sugars expressed by human gastrointestinal epithelial and immune cells<ref>PMID:19332085</ref>.  
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</StructureSection>
</StructureSection>
== 3D Structures of agglutinin ==
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|
*Agglutinin
**[[4r6r]], [[1ku8]] – jfAGG alpha+ beta-3 chains – jack fruit <br />
**[[5d5g]] – AGG - tuber <br />
**[[4uri]], [[1fny]] – RpAGG – ''Robinia pseudoacacia'' <br />
**[[4g9m]] – RsAGG – ''Rhizoctonia solani''<br />
**[[4gu8]] – BoAGG – ''Burkholderia oklahomensis''<br />
**[[4fbo]] – AGG – ''Pseudomonas fluorescens'' <br />
**[[2x2s]] – SsAGG – ''Sclerotinia sclerotiorum'' <br />
**[[4fbr]] – MxAGG – ''Myxococcus xanthus'' <br />
**[[3s5v]], [[3s60]] – OaAGG – ''Oscillatoria agardhi'' <br />
**[[3lly]] – MpAGG alpha+ beta-2 chains – ''Maclura pomifera'' <br />
**[[2ce6]] – HpAGG – ''Helix pomatia''<br />
**[[1ouw]] – AGG – hedge bindweed<br />
**[[1dlp]], [[1b2p]] – AGG – ''Scilla campanulata''<br />
**[[1c3k]] – HtAGG – ''Helianthus tuberosus''<br />
**[[1jly]] – AcAGG – ''Amaranthus caudatus''<br />
* Agglutinin complex with polysaccharide
**[[5j51]], [[5jm1]], [[4r6n]], [[4r6o]], [[4r6p]], [[4r6q]], [[4r6r]], [[4akc]], [[5j50]], [[5j4x]], [[5j4t]] – jfAGG alpha+ beta-3 chains + polysaccharide <br />
**[[5jm1]] – jfAGG alpha+ beta-3 chains + trisaccharide <br />
**[[1g9f]], [[2sba]], [[1sbd]], [[1sbe]], [[1sbf]] – soAGG + polysaccharide - soybean<br />
**[[1jlx]] – AcAGG + polysaccharide <br />
**[[4gk9]] – BoAGG + polysaccharide <br />
**[[4fbv]] – MxAGG + polysaccharide <br />
**[[3s5x]] – OaAGG + polysaccharide <br />
**[[3llz]] – MpAGG + polysaccharide <br />
**[[1c3m]], [[1c3n]] – HtAGG + polysaccharide <br />
**[[1cr7]], [[1ciw]], [[2tep]], [[1bzw]], [[2pel]], [[2dv9]], [[2dva]], [[2dvb]], [[2dvd]], [[2dvf]], [[2dvg]] – pAGG + polysaccharide - peanut<br />
**[[2x2t]] – SsAGG + polysaccharide <br />
**[[1jot]] – AGG + polysaccharide – osage orange<br />
**[[3ef2]], [[2iho]] – MoAGG + polysaccharide – ''Marasmius oreades''<br />
**[[3c9z]], [[3ca0]], [[3ca1]], [[3ca3]], [[3ca4]], [[3ca5]], [[3ca6]], [[3cah]] – AGG II + polysaccharide – ''Sambucus nigra''<br />
**[[2zmk]], [[2zml]], [[2zmn]], [[2e51]], [[2e53]], [[2e7q]], [[2e7t]], [[1f9k]], [[1wbl]] – GbAGG + polysaccharide – Goa bean<br />
**[[1jpc]], [[1niv]] – snAGG + polysaccharide – snowdrop<br />
**[[2zr1]] – IlAGG alpha+ beta chains + polysaccharide – Indian licorice<br />
**[[1ugy]], [[1uh1]] – jfAGG alpha+ beta-3 chains + polysaccharide <br />
* Agglutinin complex with monosaccharide
**[[4ak4]], [[4akb]], [[1jac]] – jfAGG alpha+ beta-3 chains + saccharide <br />
**[[5kxb]] – wiAGG + GalNAc - wisteria <br />
**[[5kxc]], [[5kxd]], [[5kxe]] – wiAGG + polysaccharide <br />
**[[5d9z]] – AGG + mannose - taro <br />
**[[3dzw]], [[1npl]] – AGG + mannose – daffodil <br />
**[[4q56]] – AGG + saccharide – ''Helix aspersa''<br />
**[[4g9n]] – RsAGG + saccharide <br />
**[[2d3s]] – GbAGG + saccharide + antigen <br />
**[[2dtw]], [[2dty]], [[2du0]], [[2du1]], [[1fay]], [[1wbf]] – GbAGG + saccharide <br />
**[[2cgz]], [[2cgy]] – HpAGG + saccharide + antigen <br />
**[[2ccv]] – HpAGG + saccharide <br />
**[[1fnz]] – RpAGG + saccharide <br />
**[[1qf3]] – pAGG + saccharide <br />
**[[2cgz]] – AGG + saccharide – ''Bowringia milbraedii''<br />
**[[1rzo]] – AGG + saccharide – ''Ricinus communis''<br />
**[[1toq]], [[1tp8]] – AGG + saccharide – ''Artocarpus hirsuta''<br />
**[[1msa]] – snAGG + saccharide <br />
**[[2q3n]] – IlAGG alpha+ beta chains + saccharide <br />
**[[1kj1]], [[1bwu]] – AGG I II chains + saccharide - garlic<br />
**[[3lm1]] – MpAGG alpha+ beta-2 chains + saccharide <br />
**[[1ws4]], [[1ws5]], [[1ugw]], [[1uh0]], [[1kuj]] – jfAGG alpha+ beta-3 chains + saccharide <br />
**[[1ugx]], [[1m26]] – jfAGG alpha+ beta-3 chains + saccharide + antigen<br />
*Agglutinin complex with other compounds
**[[5d61]], [[5d62]], [[5d63]] – MoAGG + peptide inhibitor  <br />
**[[5mu9]] – MoAGG + guanidine derivative  <br />
**[[4d69]] – soAGG + peptide  <br />
**[[1pxd]] – jfAGG alpha+ beta-3 chains + porphyrin derivative <br />
*Agglutinin isolectin
**[[7wga]], [[9wga]] – wgAGG 1 – wheat germ  <br />
**[[4aml]] – wgAGG 1 + glycosylurethan  <br />
**[[2x3t]], [[2cwg]] – wgAGG 1 + glycopeptide  <br />
**[[2uvo]] – wgAGG 1 + NAG  <br />
**[[1wgc]], [[2wgc]] – wgAGG 1+ polysaccharide  <br />
**[[1en2]], [[1enm]] – gnAGG 1 + NAG – great nettle <br />
**[[1wgt]] – wgAGG 3 <br />
**[[2x52]] – wgAGG 3 + pyranose derivative <br />
**[[1k7t]], [[1k7u]], [[1k7v]] – wgAGG 3 + polysaccharide  <br />
**[[1iqb]], [[1eis]], [[1ehd]], [[1ehh]] – gnAGG 6  <br />
**[[1ehh]] – gnAGG 6+ polysaccharide  <br />
}}


== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman
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