2cp7: Difference between revisions
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==Solution structure of the 1st CAP-Gly domain in mouse CLIP-170/restin== | ==Solution structure of the 1st CAP-Gly domain in mouse CLIP-170/restin== | ||
<StructureSection load='2cp7' size='340' side='right' caption='[[2cp7]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | <StructureSection load='2cp7' size='340' side='right' caption='[[2cp7]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
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<table><tr><td colspan='2'>[[2cp7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CP7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CP7 FirstGlance]. <br> | <table><tr><td colspan='2'>[[2cp7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CP7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CP7 FirstGlance]. <br> | ||
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RIKEN cDNA 4631429H07 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr> | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RIKEN cDNA 4631429H07 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cp7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cp7 OCA], [http://pdbe.org/2cp7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cp7 RCSB], [http://www.ebi.ac.uk/pdbsum/2cp7 PDBsum], [http://www.topsan.org/Proteins/RSGI/2cp7 TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cp7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cp7 OCA], [http://pdbe.org/2cp7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cp7 RCSB], [http://www.ebi.ac.uk/pdbsum/2cp7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2cp7 ProSAT], [http://www.topsan.org/Proteins/RSGI/2cp7 TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cp/2cp7_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cp/2cp7_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
Revision as of 11:08, 23 May 2018
Solution structure of the 1st CAP-Gly domain in mouse CLIP-170/restinSolution structure of the 1st CAP-Gly domain in mouse CLIP-170/restin
Structural highlights
Function[CLIP1_MOUSE] Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth and microtubule bundling. Links cytoplasmic vesicles to microtubules and thereby plays an important role in intracellular vesicle trafficking. Plays a role macropinocytosis and endosome trafficking (By similarity). Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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