2cp7
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Solution structure of the 1st CAP-Gly domain in mouse CLIP-170/restinSolution structure of the 1st CAP-Gly domain in mouse CLIP-170/restin
Structural highlights
FunctionCLIP1_MOUSE Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth and microtubule bundling. Links cytoplasmic vesicles to microtubules and thereby plays an important role in intracellular vesicle trafficking. Plays a role macropinocytosis and endosome trafficking (By similarity). Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. |
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